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The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy.
Am J Surg. 2009 Sep; 198(3):325-32.AJ

Abstract

BACKGROUND

Particular attention should be paid to postoperative patients that suffer from severe acute kidney injury (AKI) requiring renal replacement therapy (RRT).

METHODS

This multicenter prospective observational study included 342 patients with postoperative AKI requiring RRT from January 2002 to December 2006.

RESULTS

There were 137 (40%) survivors at 90 days after the commencement of RRT. Independent predictors of 90-day mortality were older age, presence of sepsis, status post-cardiopulmonary resuscitation, necessity of continuous renal replacement therapy (CRRT), requirement of total parenteral nutrition, lower body mass index, higher Sequential Organ Failure Assessment score, and higher serum lactate level at the commencement of RRT. Further analysis among the survivors showed that lower serum creatinine at intensive care unit admission, lower Simplified Acute Physiology Score II and inotropic equivalent score at the commencement of RRT, and using CRRT were independent predictors for subsequent renal recovery.

CONCLUSIONS

The development of AKI requiring RRT in postoperative critical patients represents a substantial risk for mortality and morbidity.

Authors+Show Affiliations

Department of Nephrology, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19716882

Citation

Lin, Yu-Feng, et al. "The 90-day Mortality and the Subsequent Renal Recovery in Critically Ill Surgical Patients Requiring Acute Renal Replacement Therapy." American Journal of Surgery, vol. 198, no. 3, 2009, pp. 325-32.
Lin YF, Ko WJ, Chu TS, et al. The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy. Am J Surg. 2009;198(3):325-32.
Lin, Y. F., Ko, W. J., Chu, T. S., Chen, Y. S., Wu, V. C., Chen, Y. M., Wu, M. S., Chen, Y. W., Tsai, C. W., Shiao, C. C., Li, W. Y., Hu, F. C., Tsai, P. R., Tsai, T. J., & Wu, K. D. (2009). The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy. American Journal of Surgery, 198(3), 325-32. https://doi.org/10.1016/j.amjsurg.2008.10.021
Lin YF, et al. The 90-day Mortality and the Subsequent Renal Recovery in Critically Ill Surgical Patients Requiring Acute Renal Replacement Therapy. Am J Surg. 2009;198(3):325-32. PubMed PMID: 19716882.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy. AU - Lin,Yu-Feng, AU - Ko,Wen-Je, AU - Chu,Tzong-Shinn, AU - Chen,Yih-Sharng, AU - Wu,Vin-Cent, AU - Chen,Yung-Ming, AU - Wu,Ming-Shiou, AU - Chen,Yung-Wei, AU - Tsai,Ching-Wei, AU - Shiao,Chih-Chung, AU - Li,Wen-Yi, AU - Hu,Fu-Chang, AU - Tsai,Pi-Ru, AU - Tsai,Tun-Jun, AU - Wu,Kwan-Dun, AU - ,, PY - 2008/09/06/received PY - 2008/10/26/revised PY - 2008/10/28/accepted PY - 2009/9/1/entrez PY - 2009/9/1/pubmed PY - 2009/9/30/medline SP - 325 EP - 32 JF - American journal of surgery JO - Am J Surg VL - 198 IS - 3 N2 - BACKGROUND: Particular attention should be paid to postoperative patients that suffer from severe acute kidney injury (AKI) requiring renal replacement therapy (RRT). METHODS: This multicenter prospective observational study included 342 patients with postoperative AKI requiring RRT from January 2002 to December 2006. RESULTS: There were 137 (40%) survivors at 90 days after the commencement of RRT. Independent predictors of 90-day mortality were older age, presence of sepsis, status post-cardiopulmonary resuscitation, necessity of continuous renal replacement therapy (CRRT), requirement of total parenteral nutrition, lower body mass index, higher Sequential Organ Failure Assessment score, and higher serum lactate level at the commencement of RRT. Further analysis among the survivors showed that lower serum creatinine at intensive care unit admission, lower Simplified Acute Physiology Score II and inotropic equivalent score at the commencement of RRT, and using CRRT were independent predictors for subsequent renal recovery. CONCLUSIONS: The development of AKI requiring RRT in postoperative critical patients represents a substantial risk for mortality and morbidity. SN - 1879-1883 UR - https://www.unboundmedicine.com/medline/citation/19716882/The_90_day_mortality_and_the_subsequent_renal_recovery_in_critically_ill_surgical_patients_requiring_acute_renal_replacement_therapy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9610(09)00005-1 DB - PRIME DP - Unbound Medicine ER -