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Charcot neuroarthropathy of the foot and ankle.
J Am Acad Orthop Surg. 2009 Sep; 17(9):562-71.JA

Abstract

Charcot neuroarthropathy is a common cause of morbidity in persons with diabetes mellitus and sensory neuropathy. Although Charcot neuroarthropathy is rare, it likely will become more prevalent in conjunction with increased incidence of diabetes mellitus. Prevention of disease progression remains the mainstay of treatment, with surgical intervention usually reserved for refractory cases. Late deformities are often complicated by chronic ulceration, infection, and osteomyelitis. The clinical presentation is best summarized with the Eichenholtz classification, and progression often follows a predictable pattern. Although Charcot neuroarthropathy is a clinical diagnosis, recent advances in diagnostic imaging have eased the clinical challenge of deciphering infection from Charcot changes. Advances in surgical treatment have demonstrated new options for limb salvage. Pharmacologic therapies directed toward decreasing bone resorption have also shown promise for treatment, but clinical application remains theoretical.

Authors+Show Affiliations

Jackson Memorial Hospital/University of Miami Orthopaedic Residency Program, Miami, FL, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19726740

Citation

van der Ven, Alexander, et al. "Charcot Neuroarthropathy of the Foot and Ankle." The Journal of the American Academy of Orthopaedic Surgeons, vol. 17, no. 9, 2009, pp. 562-71.
van der Ven A, Chapman CB, Bowker JH. Charcot neuroarthropathy of the foot and ankle. J Am Acad Orthop Surg. 2009;17(9):562-71.
van der Ven, A., Chapman, C. B., & Bowker, J. H. (2009). Charcot neuroarthropathy of the foot and ankle. The Journal of the American Academy of Orthopaedic Surgeons, 17(9), 562-71.
van der Ven A, Chapman CB, Bowker JH. Charcot Neuroarthropathy of the Foot and Ankle. J Am Acad Orthop Surg. 2009;17(9):562-71. PubMed PMID: 19726740.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Charcot neuroarthropathy of the foot and ankle. AU - van der Ven,Alexander, AU - Chapman,Cary B, AU - Bowker,John H, PY - 2009/9/4/entrez PY - 2009/9/4/pubmed PY - 2009/10/14/medline SP - 562 EP - 71 JF - The Journal of the American Academy of Orthopaedic Surgeons JO - J Am Acad Orthop Surg VL - 17 IS - 9 N2 - Charcot neuroarthropathy is a common cause of morbidity in persons with diabetes mellitus and sensory neuropathy. Although Charcot neuroarthropathy is rare, it likely will become more prevalent in conjunction with increased incidence of diabetes mellitus. Prevention of disease progression remains the mainstay of treatment, with surgical intervention usually reserved for refractory cases. Late deformities are often complicated by chronic ulceration, infection, and osteomyelitis. The clinical presentation is best summarized with the Eichenholtz classification, and progression often follows a predictable pattern. Although Charcot neuroarthropathy is a clinical diagnosis, recent advances in diagnostic imaging have eased the clinical challenge of deciphering infection from Charcot changes. Advances in surgical treatment have demonstrated new options for limb salvage. Pharmacologic therapies directed toward decreasing bone resorption have also shown promise for treatment, but clinical application remains theoretical. SN - 1067-151X UR - https://www.unboundmedicine.com/medline/citation/19726740/Charcot_neuroarthropathy_of_the_foot_and_ankle_ DB - PRIME DP - Unbound Medicine ER -