Tags

Type your tag names separated by a space and hit enter

Indoor allergens and microbial bio-contaminants in homes of asthmatic children in central Taiwan.
J Asthma 2009; 46(7):745-9JA

Abstract

Indoor allergens and microbial bio-contaminants play a significant role in asthma symptoms. The aim of the study was to determine levels of house dust mite allergens, bacterial endotoxin, and fungal beta-glucan in homes of 120 asthmatic children in central Taiwan. Dust samples from 120 mattresses (67 double-sided) were analyzed for house dust mite allergens (Der p 1, Der f 1, and Blo t 5), endotoxin, and beta-glucan. Pillows (n = 118) were analyzed for house dust mite allergens only. Kitchen dust samples were analyzed for the cockroach allergen, Bla g 1. Blo t 5 was detected in 9.3% pillows and 82.2% mattresses, Der p 1 in 95.8% pillows and 93.2% mattresses, and Der f 1 in 82.2% pillows and 83.1% mattresses. Geometric mean levels (95% confidence interval) of endotoxin and beta-glucan in mattresses were 108.4 Eu/mg (81.4-144.2) and 25.2 microg/g (22.7-28.0), respectively. House dust mite allergens and endotoxin levels were significantly lower on the bamboo side of 67 mattresses, compared to the inner sprung mattress side. Geometric mean of kitchen Bla g 1 was 0.61 U/g (95% CI: 0.43-0.85). Given the presence of Der p 1, Der f 1 and Blo t 5 in central Taiwan, it is advised to measure allergens of all three house dust mite species to obtain a true index of allergen exposure. Bamboo sides of mattresses had significantly lower house dust mite allergens and endotoxin levels.

Authors+Show Affiliations

Department of Emergency Medicine, Changhua Christian Hospital, Changhua City, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19728217

Citation

Wu, Francis Fu-Sheng, et al. "Indoor Allergens and Microbial Bio-contaminants in Homes of Asthmatic Children in Central Taiwan." The Journal of Asthma : Official Journal of the Association for the Care of Asthma, vol. 46, no. 7, 2009, pp. 745-9.
Wu FF, Siebers R, Chang CF, et al. Indoor allergens and microbial bio-contaminants in homes of asthmatic children in central Taiwan. J Asthma. 2009;46(7):745-9.
Wu, F. F., Siebers, R., Chang, C. F., Hsieh, S. W., Wu, M. W., Chen, C. Y., ... Crane, J. (2009). Indoor allergens and microbial bio-contaminants in homes of asthmatic children in central Taiwan. The Journal of Asthma : Official Journal of the Association for the Care of Asthma, 46(7), pp. 745-9. doi:10.1080/02770900903082597.
Wu FF, et al. Indoor Allergens and Microbial Bio-contaminants in Homes of Asthmatic Children in Central Taiwan. J Asthma. 2009;46(7):745-9. PubMed PMID: 19728217.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Indoor allergens and microbial bio-contaminants in homes of asthmatic children in central Taiwan. AU - Wu,Francis Fu-Sheng, AU - Siebers,Robert, AU - Chang,Chin-Fu, AU - Hsieh,Shu-Wen, AU - Wu,Mei-Wen, AU - Chen,Chi-Ying, AU - Pierse,Nevil, AU - Crane,Julian, PY - 2009/9/4/entrez PY - 2009/9/4/pubmed PY - 2009/9/29/medline SP - 745 EP - 9 JF - The Journal of asthma : official journal of the Association for the Care of Asthma JO - J Asthma VL - 46 IS - 7 N2 - Indoor allergens and microbial bio-contaminants play a significant role in asthma symptoms. The aim of the study was to determine levels of house dust mite allergens, bacterial endotoxin, and fungal beta-glucan in homes of 120 asthmatic children in central Taiwan. Dust samples from 120 mattresses (67 double-sided) were analyzed for house dust mite allergens (Der p 1, Der f 1, and Blo t 5), endotoxin, and beta-glucan. Pillows (n = 118) were analyzed for house dust mite allergens only. Kitchen dust samples were analyzed for the cockroach allergen, Bla g 1. Blo t 5 was detected in 9.3% pillows and 82.2% mattresses, Der p 1 in 95.8% pillows and 93.2% mattresses, and Der f 1 in 82.2% pillows and 83.1% mattresses. Geometric mean levels (95% confidence interval) of endotoxin and beta-glucan in mattresses were 108.4 Eu/mg (81.4-144.2) and 25.2 microg/g (22.7-28.0), respectively. House dust mite allergens and endotoxin levels were significantly lower on the bamboo side of 67 mattresses, compared to the inner sprung mattress side. Geometric mean of kitchen Bla g 1 was 0.61 U/g (95% CI: 0.43-0.85). Given the presence of Der p 1, Der f 1 and Blo t 5 in central Taiwan, it is advised to measure allergens of all three house dust mite species to obtain a true index of allergen exposure. Bamboo sides of mattresses had significantly lower house dust mite allergens and endotoxin levels. SN - 1532-4303 UR - https://www.unboundmedicine.com/medline/citation/19728217/Indoor_allergens_and_microbial_bio_contaminants_in_homes_of_asthmatic_children_in_central_Taiwan_ L2 - http://www.tandfonline.com/doi/full/10.1080/02770900903082597 DB - PRIME DP - Unbound Medicine ER -