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A new iridoid glycoside from Scrophularia ningpoensis.
Nat Prod Res. 2009; 23(13):1181-8.NP

Abstract

A new iridoid glycoside, named 6'-O-cinnamoylharpagide (1), has been isolated from the roots of Scrophularia ningpoensis (Scrophulariaceae) together with nine known compounds, harpagide (2), harpagoside (3), 8-O-feruloylharpagide (4), 8-O-(p-coumaroyl)harpagide (5), 6-O-methylcatalpol (6), aucubin (7), buergerinin B (8), teuhircoside (9) and 6-O-cinnamoyl-D-glucopyranose (10). Compound 10 was obtained as an inseparable mixture of 6-O-cinnamoyl-alpha-D-glucopyranose and 6-O-cinnamoyl-beta-D-glucopyranose at a ratio of 1 : 1, which is presumably formed by cleavage of compound 1. Their structures were elucidated on the basis of chemical and spectral analysis.

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Authors+Show Affiliations

Niu ZR
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Centre, Beijing, P.R. China.
Wang RF
No affiliation info available
Shang MY
No affiliation info available
Cai SQ
No affiliation info available

MeSH

Chromatography, High Pressure LiquidGlycosidesIridoidsMagnetic Resonance SpectroscopyMolecular StructureScrophularia

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19731136

Citation

Niu, Zheng-Rui, et al. "A New Iridoid Glycoside From Scrophularia Ningpoensis." Natural Product Research, vol. 23, no. 13, 2009, pp. 1181-8.
Niu ZR, Wang RF, Shang MY, et al. A new iridoid glycoside from Scrophularia ningpoensis. Nat Prod Res. 2009;23(13):1181-8.
Niu, Z. R., Wang, R. F., Shang, M. Y., & Cai, S. Q. (2009). A new iridoid glycoside from Scrophularia ningpoensis. Natural Product Research, 23(13), 1181-8. https://doi.org/10.1080/14786410802386344
Niu ZR, et al. A New Iridoid Glycoside From Scrophularia Ningpoensis. Nat Prod Res. 2009;23(13):1181-8. PubMed PMID: 19731136.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new iridoid glycoside from Scrophularia ningpoensis. AU - Niu,Zheng-Rui, AU - Wang,Ru-Feng, AU - Shang,Ming-Ying, AU - Cai,Shao-Qing, PY - 2009/9/5/entrez PY - 2009/9/5/pubmed PY - 2009/12/16/medline SP - 1181 EP - 8 JF - Natural product research JO - Nat Prod Res VL - 23 IS - 13 N2 - A new iridoid glycoside, named 6'-O-cinnamoylharpagide (1), has been isolated from the roots of Scrophularia ningpoensis (Scrophulariaceae) together with nine known compounds, harpagide (2), harpagoside (3), 8-O-feruloylharpagide (4), 8-O-(p-coumaroyl)harpagide (5), 6-O-methylcatalpol (6), aucubin (7), buergerinin B (8), teuhircoside (9) and 6-O-cinnamoyl-D-glucopyranose (10). Compound 10 was obtained as an inseparable mixture of 6-O-cinnamoyl-alpha-D-glucopyranose and 6-O-cinnamoyl-beta-D-glucopyranose at a ratio of 1 : 1, which is presumably formed by cleavage of compound 1. Their structures were elucidated on the basis of chemical and spectral analysis. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/19731136/A_new_iridoid_glycoside_from_Scrophularia_ningpoensis_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410802386344 DB - PRIME DP - Unbound Medicine ER -