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Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala.
Nat Prod Commun. 2009 Jul; 4(7):993-6.NP

Abstract

The essential oil composition of the aerial parts of Anaphalis nubigena DC. var. monocephala (DC.) C. B. Clarke collected from Pindari glacier at a height of 3300 m, was analyzed by using GC and GC/MS. Sixty components were identified, accounting for 95.9% of the total oil. The main constituents were alpha-guaiene (12.3%), gamma-muurolene (10.4%), gamma-cadinene (8.3%), alpha-muurolol (7.4%), alpha-gurjunene (6.0%) and alpha-bulnesene (5.8%). The oil was found to be rich in sesquiterpene hydrocarbons (60.1%). The oil was active against Escherichia coli (NCIM 2065) and Klebsiella pneumoniae (NCIM 2957), with MIC values of 125 microg/mL and 500 microg/mL, respectively.

Authors+Show Affiliations

Joshi RK
Regional Medical Research Center, Indian Council of Medical Research, Belgaum, Karnataka-590 010, India. joshirk_natprod@yahoo.com
Pande C
No affiliation info available
Mujawar MH
No affiliation info available
Kholkute SD
No affiliation info available

MeSH

Anti-Bacterial AgentsAsteraceaeBacteriaGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsOils, Volatile

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19731610

Citation

Joshi, Rajesh K., et al. "Chemical Composition and Antimicrobial Activity of the Essential Oil of Anaphalis Nubigena Var. Monocephala." Natural Product Communications, vol. 4, no. 7, 2009, pp. 993-6.
Joshi RK, Pande C, Mujawar MH, et al. Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala. Nat Prod Commun. 2009;4(7):993-6.
Joshi, R. K., Pande, C., Mujawar, M. H., & Kholkute, S. D. (2009). Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala. Natural Product Communications, 4(7), 993-6.
Joshi RK, et al. Chemical Composition and Antimicrobial Activity of the Essential Oil of Anaphalis Nubigena Var. Monocephala. Nat Prod Commun. 2009;4(7):993-6. PubMed PMID: 19731610.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antimicrobial activity of the essential oil of Anaphalis nubigena var. monocephala. AU - Joshi,Rajesh K, AU - Pande,Chitra, AU - Mujawar,Mohammad H K, AU - Kholkute,Sanjiva D, PY - 2009/9/8/entrez PY - 2009/9/8/pubmed PY - 2009/9/30/medline SP - 993 EP - 6 JF - Natural product communications JO - Nat Prod Commun VL - 4 IS - 7 N2 - The essential oil composition of the aerial parts of Anaphalis nubigena DC. var. monocephala (DC.) C. B. Clarke collected from Pindari glacier at a height of 3300 m, was analyzed by using GC and GC/MS. Sixty components were identified, accounting for 95.9% of the total oil. The main constituents were alpha-guaiene (12.3%), gamma-muurolene (10.4%), gamma-cadinene (8.3%), alpha-muurolol (7.4%), alpha-gurjunene (6.0%) and alpha-bulnesene (5.8%). The oil was found to be rich in sesquiterpene hydrocarbons (60.1%). The oil was active against Escherichia coli (NCIM 2065) and Klebsiella pneumoniae (NCIM 2957), with MIC values of 125 microg/mL and 500 microg/mL, respectively. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/19731610/Chemical_composition_and_antimicrobial_activity_of_the_essential_oil_of_Anaphalis_nubigena_var__monocephala_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -