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Immune response to measles vaccine after mass vaccination in Urmia, Islamic Republic of Iran.
East Mediterr Health J. 2009 May-Jun; 15(3):516-25.EM

Abstract

We investigated the effectiveness of the mass measles vaccination campaign in Urmia, Islamic Republic of Iran, by examining the measles IgG seroprevalence and antibody response from paired data before and after the campaign. The overall seropositive rate of 624 subjects aged 5-25 years increased 1 year after the mass vaccination (from 53.0% to 72.3%). A rise in antibody titre occurred in all age groups except the 21-25 years group, which had the highest titre before mass vaccination. On logistic regression analysis, only immune status prior to vaccination was significantly associated with the seroresponse. It may be cost-effective to check antibody titres before mass vaccinations, especially in high vaccine coverage regions with circulating wild virus.

Authors+Show Affiliations

Department of Community Medicine, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Islamic Republic of Iran. yekta42@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19731767

Citation

Yekta, Z, et al. "Immune Response to Measles Vaccine After Mass Vaccination in Urmia, Islamic Republic of Iran." Eastern Mediterranean Health Journal = La Revue De Sante De La Mediterranee Orientale = al-Majallah Al-sihhiyah Li-sharq Al-mutawassit, vol. 15, no. 3, 2009, pp. 516-25.
Yekta Z, Pourali R, Taravati MR, et al. Immune response to measles vaccine after mass vaccination in Urmia, Islamic Republic of Iran. East Mediterr Health J. 2009;15(3):516-25.
Yekta, Z., Pourali, R., Taravati, M. R., Shahabi, S., Salary, S., Khalily, F., & Farzin, A. (2009). Immune response to measles vaccine after mass vaccination in Urmia, Islamic Republic of Iran. Eastern Mediterranean Health Journal = La Revue De Sante De La Mediterranee Orientale = al-Majallah Al-sihhiyah Li-sharq Al-mutawassit, 15(3), 516-25.
Yekta Z, et al. Immune Response to Measles Vaccine After Mass Vaccination in Urmia, Islamic Republic of Iran. East Mediterr Health J. 2009 May-Jun;15(3):516-25. PubMed PMID: 19731767.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immune response to measles vaccine after mass vaccination in Urmia, Islamic Republic of Iran. AU - Yekta,Z, AU - Pourali,R, AU - Taravati,M R, AU - Shahabi,S, AU - Salary,S, AU - Khalily,F, AU - Farzin,A, PY - 2009/9/8/entrez PY - 2009/9/8/pubmed PY - 2009/10/16/medline SP - 516 EP - 25 JF - Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit JO - East Mediterr Health J VL - 15 IS - 3 N2 - We investigated the effectiveness of the mass measles vaccination campaign in Urmia, Islamic Republic of Iran, by examining the measles IgG seroprevalence and antibody response from paired data before and after the campaign. The overall seropositive rate of 624 subjects aged 5-25 years increased 1 year after the mass vaccination (from 53.0% to 72.3%). A rise in antibody titre occurred in all age groups except the 21-25 years group, which had the highest titre before mass vaccination. On logistic regression analysis, only immune status prior to vaccination was significantly associated with the seroresponse. It may be cost-effective to check antibody titres before mass vaccinations, especially in high vaccine coverage regions with circulating wild virus. SN - 1020-3397 UR - https://www.unboundmedicine.com/medline/citation/19731767/Immune_response_to_measles_vaccine_after_mass_vaccination_in_Urmia_Islamic_Republic_of_Iran_ L2 - http://applications.emro.who.int/emhj/1503/15_3_2009_0516_0525.pdf DB - PRIME DP - Unbound Medicine ER -