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Intrathecal baclofen use in adults with cerebral palsy.
Dev Med Child Neurol. 2009 Oct; 51 Suppl 4:106-12.DM

Abstract

Intrathecal baclofen (ITB) is an effective treatment for both spasticity and dystonia in people with cerebral palsy (CP). Its use is becoming increasingly common. ITB is typically associated with fewer side effects than the oral form of the product, but there are risks related to the hardware needed for intrathecal delivery. Much of what has been reported in the literature about ITB is based on experience with children or groups of children and adults; few reports exclusively address its use in adults with CP. These reports indicate that muscle tone is consistently reduced, but there is some variability in functional outcomes. Few well-controlled studies have been done. Controversies remain concerning ITB, including whether a trial is needed before pump implantation, proper catheter tip placement, and programming options, as well as whether it contributes to the development or progression of scoliosis. These and other unanswered questions should be addressed in a systematic way.

Authors+Show Affiliations

Department of Physical Medicine and Rehabilitation, University of Minnesota, Minneapolis, 55455, USA. krach002@umn.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19740217

Citation

Krach, Linda E.. "Intrathecal Baclofen Use in Adults With Cerebral Palsy." Developmental Medicine and Child Neurology, vol. 51 Suppl 4, 2009, pp. 106-12.
Krach LE. Intrathecal baclofen use in adults with cerebral palsy. Dev Med Child Neurol. 2009;51 Suppl 4:106-12.
Krach, L. E. (2009). Intrathecal baclofen use in adults with cerebral palsy. Developmental Medicine and Child Neurology, 51 Suppl 4, 106-12. https://doi.org/10.1111/j.1469-8749.2009.03422.x
Krach LE. Intrathecal Baclofen Use in Adults With Cerebral Palsy. Dev Med Child Neurol. 2009;51 Suppl 4:106-12. PubMed PMID: 19740217.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intrathecal baclofen use in adults with cerebral palsy. A1 - Krach,Linda E, PY - 2009/9/11/entrez PY - 2009/9/18/pubmed PY - 2009/10/7/medline SP - 106 EP - 12 JF - Developmental medicine and child neurology JO - Dev Med Child Neurol VL - 51 Suppl 4 N2 - Intrathecal baclofen (ITB) is an effective treatment for both spasticity and dystonia in people with cerebral palsy (CP). Its use is becoming increasingly common. ITB is typically associated with fewer side effects than the oral form of the product, but there are risks related to the hardware needed for intrathecal delivery. Much of what has been reported in the literature about ITB is based on experience with children or groups of children and adults; few reports exclusively address its use in adults with CP. These reports indicate that muscle tone is consistently reduced, but there is some variability in functional outcomes. Few well-controlled studies have been done. Controversies remain concerning ITB, including whether a trial is needed before pump implantation, proper catheter tip placement, and programming options, as well as whether it contributes to the development or progression of scoliosis. These and other unanswered questions should be addressed in a systematic way. SN - 1469-8749 UR - https://www.unboundmedicine.com/medline/citation/19740217/Intrathecal_baclofen_use_in_adults_with_cerebral_palsy_ L2 - https://doi.org/10.1111/j.1469-8749.2009.03422.x DB - PRIME DP - Unbound Medicine ER -