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Epidemiology of typhoid and paratyphoid fever in India.
J Infect Dev Ctries. 2008 Dec 01; 2(6):454-60.JI

Abstract

Enteric fever (typhoid and paratyphoid fever) is a major human bacterial infection. Although the disease is not common in industrialised countries, it remains an important and persistent health problem in developing nations. Hospital-based studies and outbreak reports from India indicate that enteric fever is a major public health problem in this country, with Salmonella enterica serovar Typhi (S. Typhi) the most common aetiologic agent but with an apparently increasing number of cases due to S. Paratyphi A (SPA). Because risk factors such as poor sanitation, lack of a safe drinking water supply and low socio economic conditions in resource-poor countries are amplified by the evolution of multidrug resistant salmonellae with reduced susceptibility to fluoroquinolone, treatment failure cases have been reported in India, which is associated with increased mortality and morbidity. Vaccination, which requires strict planning and proper targeting of the vulnerable age groups, is considered to be an effective tool in controlling this disease in endemic areas, given there is development of a conjugate vaccine against both serovars (S. Typhi and S. Para A).

Authors+Show Affiliations

Division of Epidemiology, National Institute of Cholera and Enteric Diseases, Kolkata, India, Beliaghata, Kolkata-700010, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19745523

Citation

Kanungo, Suman, et al. "Epidemiology of Typhoid and Paratyphoid Fever in India." Journal of Infection in Developing Countries, vol. 2, no. 6, 2008, pp. 454-60.
Kanungo S, Dutta S, Sur D. Epidemiology of typhoid and paratyphoid fever in India. J Infect Dev Ctries. 2008;2(6):454-60.
Kanungo, S., Dutta, S., & Sur, D. (2008). Epidemiology of typhoid and paratyphoid fever in India. Journal of Infection in Developing Countries, 2(6), 454-60.
Kanungo S, Dutta S, Sur D. Epidemiology of Typhoid and Paratyphoid Fever in India. J Infect Dev Ctries. 2008 Dec 1;2(6):454-60. PubMed PMID: 19745523.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology of typhoid and paratyphoid fever in India. AU - Kanungo,Suman, AU - Dutta,Shanta, AU - Sur,Dipika, Y1 - 2008/12/01/ PY - 2008/06/14/received PY - 2009/9/12/entrez PY - 2008/1/1/pubmed PY - 2009/12/16/medline SP - 454 EP - 60 JF - Journal of infection in developing countries JO - J Infect Dev Ctries VL - 2 IS - 6 N2 - Enteric fever (typhoid and paratyphoid fever) is a major human bacterial infection. Although the disease is not common in industrialised countries, it remains an important and persistent health problem in developing nations. Hospital-based studies and outbreak reports from India indicate that enteric fever is a major public health problem in this country, with Salmonella enterica serovar Typhi (S. Typhi) the most common aetiologic agent but with an apparently increasing number of cases due to S. Paratyphi A (SPA). Because risk factors such as poor sanitation, lack of a safe drinking water supply and low socio economic conditions in resource-poor countries are amplified by the evolution of multidrug resistant salmonellae with reduced susceptibility to fluoroquinolone, treatment failure cases have been reported in India, which is associated with increased mortality and morbidity. Vaccination, which requires strict planning and proper targeting of the vulnerable age groups, is considered to be an effective tool in controlling this disease in endemic areas, given there is development of a conjugate vaccine against both serovars (S. Typhi and S. Para A). SN - 1972-2680 UR - https://www.unboundmedicine.com/medline/citation/19745523/Epidemiology_of_typhoid_and_paratyphoid_fever_in_India_ L2 - http://www.jidc.org/index.php/journal/article/view/19745523 DB - PRIME DP - Unbound Medicine ER -