Tags

Type your tag names separated by a space and hit enter

Primitive neuroectodermal tumor of the pelvis in an elderly patient.
Onkologie. 2009 Sep; 32(8-9):499-502.O

Abstract

BACKGROUND

Peripheral primitive neuroectodermal tumors (PNET) belong to the rare family of primary bone neoplasms. Recent clinicopathological studies have revealed that Ewing's sarcoma and PNET have overlapping features and they are now included in the same classification, the Ewing's sarcoma family of tumors (EFTs). PNET have a marked predilection for the extremities and are very rare in the pelvis. These tumors can occur at any age with a peak of incidence in the second and third decades but are very rare in patients over 40 years.

CASE REPORT

We report the case of a 69-year-old man with PNET sarcoma. Outcome was favorable after combined modality treatment including chemotherapy based on the Memphis protocol - adapted from that used for Ewing's sarcoma in children - and surgery.

CONCLUSION

Our case is uncommon because of the age at diagnosis, the fortuitous way of revelation, and the choice of dose-intense chemotherapy adapted from the Memphis protocol (cyclophosphamide- and doxorubicin-based) for children, which was efficient and safe. It supports the fact that an adult, and even an old patient, with good physical status, may be treated safely and radically even with dose-adapted aggressive chemotherapy.

Authors+Show Affiliations

Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19745594

Citation

Saada, Esma, et al. "Primitive Neuroectodermal Tumor of the Pelvis in an Elderly Patient." Onkologie, vol. 32, no. 8-9, 2009, pp. 499-502.
Saada E, Thariat J, Follana P, et al. Primitive neuroectodermal tumor of the pelvis in an elderly patient. Onkologie. 2009;32(8-9):499-502.
Saada, E., Thariat, J., Follana, P., Birtwisle-Peyrottes, I., Haudebourg, J., Trojani, C., Bacque, P., & Thyss, A. (2009). Primitive neuroectodermal tumor of the pelvis in an elderly patient. Onkologie, 32(8-9), 499-502. https://doi.org/10.1159/000226585
Saada E, et al. Primitive Neuroectodermal Tumor of the Pelvis in an Elderly Patient. Onkologie. 2009;32(8-9):499-502. PubMed PMID: 19745594.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Primitive neuroectodermal tumor of the pelvis in an elderly patient. AU - Saada,Esma, AU - Thariat,Juliette, AU - Follana,Philippe, AU - Birtwisle-Peyrottes,Isabelle, AU - Haudebourg,Juliette, AU - Trojani,Christophe, AU - Bacque,Patrick, AU - Thyss,Antoine, Y1 - 2009/07/20/ PY - 2009/9/12/entrez PY - 2009/9/12/pubmed PY - 2009/12/16/medline SP - 499 EP - 502 JF - Onkologie JO - Onkologie VL - 32 IS - 8-9 N2 - BACKGROUND: Peripheral primitive neuroectodermal tumors (PNET) belong to the rare family of primary bone neoplasms. Recent clinicopathological studies have revealed that Ewing's sarcoma and PNET have overlapping features and they are now included in the same classification, the Ewing's sarcoma family of tumors (EFTs). PNET have a marked predilection for the extremities and are very rare in the pelvis. These tumors can occur at any age with a peak of incidence in the second and third decades but are very rare in patients over 40 years. CASE REPORT: We report the case of a 69-year-old man with PNET sarcoma. Outcome was favorable after combined modality treatment including chemotherapy based on the Memphis protocol - adapted from that used for Ewing's sarcoma in children - and surgery. CONCLUSION: Our case is uncommon because of the age at diagnosis, the fortuitous way of revelation, and the choice of dose-intense chemotherapy adapted from the Memphis protocol (cyclophosphamide- and doxorubicin-based) for children, which was efficient and safe. It supports the fact that an adult, and even an old patient, with good physical status, may be treated safely and radically even with dose-adapted aggressive chemotherapy. SN - 1423-0240 UR - https://www.unboundmedicine.com/medline/citation/19745594/Primitive_neuroectodermal_tumor_of_the_pelvis_in_an_elderly_patient_ L2 - https://www.karger.com?DOI=10.1159/000226585 DB - PRIME DP - Unbound Medicine ER -