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A review on mouth dissolving films.
Curr Drug Deliv. 2009 Oct; 6(5):469-76.CD

Abstract

The ultimate goal of any drug delivery system is the successful delivery of the drug to the body; however, patient compliance must not be overlooked. Fast dissolving drug delivery systems, such as, Mouth Dissolving Films (MDF), offer a convenient way of dosing medications, not only to special population groups with swallowing difficulties such as children and the elderly, but also to the general population. MDF are the novel dosage forms that disintegrate and dissolve within the oral cavity. Intra-oral absorption permits rapid onset of action and helps by-pass first-pass effects, thereby reducing the unit dose required to produce desired therapeutic effect. The present review provides an overview of various polymers that can be employed in the manufacture of MDF and highlights the effect of polymers and plasticizers on various physico-mechanical properties of MDF. It further gives a brief account of formulation of MDF and problems faced during its manufacture.

Authors+Show Affiliations

National Institute of Pharmaceutical Education and Research (NIPER)-Ahmedabad. C/o. B.V. Patel Pharmaceutical Education and Research Development Centre, S.G. Highway, Thaltej, Ahmedabad-380054, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19751197

Citation

Dahiya, Meenu, et al. "A Review On Mouth Dissolving Films." Current Drug Delivery, vol. 6, no. 5, 2009, pp. 469-76.
Dahiya M, Saha S, Shahiwala AF. A review on mouth dissolving films. Curr Drug Deliv. 2009;6(5):469-76.
Dahiya, M., Saha, S., & Shahiwala, A. F. (2009). A review on mouth dissolving films. Current Drug Delivery, 6(5), 469-76.
Dahiya M, Saha S, Shahiwala AF. A Review On Mouth Dissolving Films. Curr Drug Deliv. 2009;6(5):469-76. PubMed PMID: 19751197.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A review on mouth dissolving films. AU - Dahiya,Meenu, AU - Saha,Sumit, AU - Shahiwala,Aliasgar F, PY - 2009/04/28/received PY - 2009/06/17/accepted PY - 2009/9/16/entrez PY - 2009/9/16/pubmed PY - 2010/3/10/medline SP - 469 EP - 76 JF - Current drug delivery JO - Curr Drug Deliv VL - 6 IS - 5 N2 - The ultimate goal of any drug delivery system is the successful delivery of the drug to the body; however, patient compliance must not be overlooked. Fast dissolving drug delivery systems, such as, Mouth Dissolving Films (MDF), offer a convenient way of dosing medications, not only to special population groups with swallowing difficulties such as children and the elderly, but also to the general population. MDF are the novel dosage forms that disintegrate and dissolve within the oral cavity. Intra-oral absorption permits rapid onset of action and helps by-pass first-pass effects, thereby reducing the unit dose required to produce desired therapeutic effect. The present review provides an overview of various polymers that can be employed in the manufacture of MDF and highlights the effect of polymers and plasticizers on various physico-mechanical properties of MDF. It further gives a brief account of formulation of MDF and problems faced during its manufacture. SN - 1875-5704 UR - https://www.unboundmedicine.com/medline/citation/19751197/A_review_on_mouth_dissolving_films_ L2 - http://www.eurekaselect.com/70590/article DB - PRIME DP - Unbound Medicine ER -