Tags

Type your tag names separated by a space and hit enter

Benzoyl peroxide: a review of its current use in the treatment of acne vulgaris.
Expert Opin Pharmacother. 2009 Oct; 10(15):2555-62.EO

Abstract

BACKGROUND

Owing to the use of topical and systemic antibiotics for acne vulgaris, the incidence of antibiotic-resistant Propionibacterium acnes is increasing worldwide. Topical benzoyl peroxide (BPO) is an alternative to antibiotics in the treatment of acne vulgaris.

OBJECTIVE

This review describes and evaluates recent clinical literature regarding the efficacy and tolerability of BPO.

METHODS

A PubMed literature search was conducted using the keywords benzoyl peroxide, acne, and combination therapy.

RESULTS

BPO is equally effective at concentrations of 2.5, 5.0 and 10%. However, a concentration-dependent irritant dermatitis can occur with higher concentrations. The efficacy of BPO can be enhanced when used in combination with topical retinoids, antibiotics and tertiary amines. BPO-containing combinations do not induce bacterial resistance and are important first-line treatments for mild to moderate acne vulgaris.

Authors+Show Affiliations

Department of Dermatology, Wake Forest University School of Medicine, Center for Dermatology Research, Winston-Salem, NC 27157-1071, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19761357

Citation

Sagransky, Matt, et al. "Benzoyl Peroxide: a Review of Its Current Use in the Treatment of Acne Vulgaris." Expert Opinion On Pharmacotherapy, vol. 10, no. 15, 2009, pp. 2555-62.
Sagransky M, Yentzer BA, Feldman SR. Benzoyl peroxide: a review of its current use in the treatment of acne vulgaris. Expert Opin Pharmacother. 2009;10(15):2555-62.
Sagransky, M., Yentzer, B. A., & Feldman, S. R. (2009). Benzoyl peroxide: a review of its current use in the treatment of acne vulgaris. Expert Opinion On Pharmacotherapy, 10(15), 2555-62. https://doi.org/10.1517/14656560903277228
Sagransky M, Yentzer BA, Feldman SR. Benzoyl Peroxide: a Review of Its Current Use in the Treatment of Acne Vulgaris. Expert Opin Pharmacother. 2009;10(15):2555-62. PubMed PMID: 19761357.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Benzoyl peroxide: a review of its current use in the treatment of acne vulgaris. AU - Sagransky,Matt, AU - Yentzer,Brad A, AU - Feldman,Steven R, PY - 2009/9/19/entrez PY - 2009/9/19/pubmed PY - 2009/11/18/medline SP - 2555 EP - 62 JF - Expert opinion on pharmacotherapy JO - Expert Opin Pharmacother VL - 10 IS - 15 N2 - BACKGROUND: Owing to the use of topical and systemic antibiotics for acne vulgaris, the incidence of antibiotic-resistant Propionibacterium acnes is increasing worldwide. Topical benzoyl peroxide (BPO) is an alternative to antibiotics in the treatment of acne vulgaris. OBJECTIVE: This review describes and evaluates recent clinical literature regarding the efficacy and tolerability of BPO. METHODS: A PubMed literature search was conducted using the keywords benzoyl peroxide, acne, and combination therapy. RESULTS: BPO is equally effective at concentrations of 2.5, 5.0 and 10%. However, a concentration-dependent irritant dermatitis can occur with higher concentrations. The efficacy of BPO can be enhanced when used in combination with topical retinoids, antibiotics and tertiary amines. BPO-containing combinations do not induce bacterial resistance and are important first-line treatments for mild to moderate acne vulgaris. SN - 1744-7666 UR - https://www.unboundmedicine.com/medline/citation/19761357/Benzoyl_peroxide:_a_review_of_its_current_use_in_the_treatment_of_acne_vulgaris_ L2 - https://www.tandfonline.com/doi/full/10.1517/14656560903277228 DB - PRIME DP - Unbound Medicine ER -