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[How to investigate and diagnose autochthonous hepatitis E?].
Gastroenterol Clin Biol. 2009 Oct; 33(10-11 Suppl):F27-35.GC

Abstract

In developed countries, HEV infection was still recently considered as rare, and as an imported disease from endemic areas by travellers. Hepatitis E virus is now recognized mainly as an autochthonous disease in these countries. Although the source and the route of contamination remain uncertain, several cases of food-borne (zoonotic transmission) and blood-borne transmission have been recently reported. The mortality rates in industrialized countries seems to be higher than in endemic areas, since the infection occurs more frequently in elderly people with underlying chronic liver disease (mortality rate approaching 70% in this subgroup of patients). By contrast, whereas mortality rate rises by 20% during pregnancy in developing countries, no death in pregnant woman from developed countries secondary to an autochthonous case has been reported so far. Lastly, HEV infection may be a cause of chronic hepatitis in immunocompromised patients (mostly in solid organ-transplant recipients) which can evolve to cirrhosis.

Authors+Show Affiliations

Hôpital de Jour, centre hospitalier de Hyères, rue du Maréchal-Juin, Hyères, France. crenou@ch-hyeres.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Comparative Study
English Abstract
Journal Article

Language

fre

PubMed ID

19762188

Citation

Renou, C, et al. "[How to Investigate and Diagnose Autochthonous Hepatitis E?]." Gastroenterologie Clinique Et Biologique, vol. 33, no. 10-11 Suppl, 2009, pp. F27-35.
Renou C, Nicand E, Pariente A, et al. [How to investigate and diagnose autochthonous hepatitis E?]. Gastroenterol Clin Biol. 2009;33(10-11 Suppl):F27-35.
Renou, C., Nicand, E., Pariente, A., Cadranel, J. F., & Pavio, N. (2009). [How to investigate and diagnose autochthonous hepatitis E?]. Gastroenterologie Clinique Et Biologique, 33(10-11 Suppl), F27-35. https://doi.org/10.1016/j.gcb.2009.07.026
Renou C, et al. [How to Investigate and Diagnose Autochthonous Hepatitis E?]. Gastroenterol Clin Biol. 2009;33(10-11 Suppl):F27-35. PubMed PMID: 19762188.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [How to investigate and diagnose autochthonous hepatitis E?]. AU - Renou,C, AU - Nicand,E, AU - Pariente,A, AU - Cadranel,J-F, AU - Pavio,N, Y1 - 2009/09/16/ PY - 2009/9/19/entrez PY - 2009/9/19/pubmed PY - 2010/4/28/medline SP - F27 EP - 35 JF - Gastroenterologie clinique et biologique JO - Gastroenterol Clin Biol VL - 33 IS - 10-11 Suppl N2 - In developed countries, HEV infection was still recently considered as rare, and as an imported disease from endemic areas by travellers. Hepatitis E virus is now recognized mainly as an autochthonous disease in these countries. Although the source and the route of contamination remain uncertain, several cases of food-borne (zoonotic transmission) and blood-borne transmission have been recently reported. The mortality rates in industrialized countries seems to be higher than in endemic areas, since the infection occurs more frequently in elderly people with underlying chronic liver disease (mortality rate approaching 70% in this subgroup of patients). By contrast, whereas mortality rate rises by 20% during pregnancy in developing countries, no death in pregnant woman from developed countries secondary to an autochthonous case has been reported so far. Lastly, HEV infection may be a cause of chronic hepatitis in immunocompromised patients (mostly in solid organ-transplant recipients) which can evolve to cirrhosis. SN - 0399-8320 UR - https://www.unboundmedicine.com/medline/citation/19762188/[How_to_investigate_and_diagnose_autochthonous_hepatitis_E]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0399-8320(09)00291-7 DB - PRIME DP - Unbound Medicine ER -