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Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany.
Clin Microbiol Infect. 2010 Jun; 16(6):613-6.CM

Abstract

In a total of 167 respiratory tract specimens from adult outpatients with confirmed Mycoplasma pneumoniae pneumonia, sampled between 2003 and 2008, and a further 99 isolates obtained from patients between 1991 and 2009 in Germany, M. pneumoniae was tested for macrolide resistance. Using PCR, real-time PCR and sequencing of the 23S rRNA gene, 1.2% of M. pneumoniae in the respiratory tract samples and 3.0% of the isolates were found to be resistant. The results indicate a limited but not negligible importance of macrolide-resistant M. pneumoniae in the population investigated, which requires the monitoring of macrolide susceptibility of isolates or the testing of respiratory samples by molecular methods.

Authors+Show Affiliations

Dresden University of Technology, Medical Faculty Carl Gustav Carus, Institute of Medical Microbiology and Hygiene, Dresden. roger.dumke@tu-dresden.deNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19765022

Citation

Dumke, R, et al. "Occurrence of Macrolide-resistant Mycoplasma Pneumoniae Strains in Germany." Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, vol. 16, no. 6, 2010, pp. 613-6.
Dumke R, von Baum H, Lück PC, et al. Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany. Clin Microbiol Infect. 2010;16(6):613-6.
Dumke, R., von Baum, H., Lück, P. C., & Jacobs, E. (2010). Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 16(6), 613-6. https://doi.org/10.1111/j.1469-0691.2009.02968.x
Dumke R, et al. Occurrence of Macrolide-resistant Mycoplasma Pneumoniae Strains in Germany. Clin Microbiol Infect. 2010;16(6):613-6. PubMed PMID: 19765022.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany. AU - Dumke,R, AU - von Baum,H, AU - Lück,P C, AU - Jacobs,E, Y1 - 2009/09/17/ PY - 2009/9/22/entrez PY - 2009/9/22/pubmed PY - 2011/1/19/medline SP - 613 EP - 6 JF - Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases JO - Clin Microbiol Infect VL - 16 IS - 6 N2 - In a total of 167 respiratory tract specimens from adult outpatients with confirmed Mycoplasma pneumoniae pneumonia, sampled between 2003 and 2008, and a further 99 isolates obtained from patients between 1991 and 2009 in Germany, M. pneumoniae was tested for macrolide resistance. Using PCR, real-time PCR and sequencing of the 23S rRNA gene, 1.2% of M. pneumoniae in the respiratory tract samples and 3.0% of the isolates were found to be resistant. The results indicate a limited but not negligible importance of macrolide-resistant M. pneumoniae in the population investigated, which requires the monitoring of macrolide susceptibility of isolates or the testing of respiratory samples by molecular methods. SN - 1469-0691 UR - https://www.unboundmedicine.com/medline/citation/19765022/Occurrence_of_macrolide_resistant_Mycoplasma_pneumoniae_strains_in_Germany_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1198-743X(14)61698-0 DB - PRIME DP - Unbound Medicine ER -