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Bioavailability of catechins from ready-to-drink tea.
Nutrition. 2010 May; 26(5):528-33.N

Abstract

OBJECTIVE

Because consumption of teas may be associated with potential health benefits due to its content in polyphenols and in Western countries the consumption of tea is equally divided between the hot and the ready-to-drink (RTD) cold versions of this typical beverage, the aim of this work was to study the absorption and metabolism of flavan-3-ols in human volunteers after the ingestion of a commercial RTD tea.

METHODS

A feeding study was carried out in 20 healthy human volunteers and urine samples were collected for 24h after tea ingestion. Flavan-3-ols-derived molecules were identified and quantified in urine samples by high-performance liquid chromatography with tandem mass spectrometric detection.

RESULTS

Eight relevant metabolites were identified in urine, all modified flavan-3-ols with the exception of unmetabolized gallic acid. The urinary excretion of flavan-3-ols was equal to 7.2% of the intake with tea. Gallic acid, which was abundant in the RTD tea used in this study, reached a 4.5% of the drunken amount.

CONCLUSIONS

The bioavailability values observed are in agreement with previous reports, although the dosage of polyphenols ingested in this study is remarkably lower. Moreover, the use of a group of 20 volunteers, more than the average number of subjects used for usual human acute-feeding studies involving polyphenols, provides additional credibility to the results. After drinking the RTD ice tea used in this study, the internal compartments are exposed to non-marginal doses of flavanols and flavanol metabolites up to 24h.

Authors+Show Affiliations

Department of Public Health, University of Parma, Parma, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19765952

Citation

Del Rio, Daniele, et al. "Bioavailability of Catechins From Ready-to-drink Tea." Nutrition (Burbank, Los Angeles County, Calif.), vol. 26, no. 5, 2010, pp. 528-33.
Del Rio D, Calani L, Scazzina F, et al. Bioavailability of catechins from ready-to-drink tea. Nutrition. 2010;26(5):528-33.
Del Rio, D., Calani, L., Scazzina, F., Jechiu, L., Cordero, C., & Brighenti, F. (2010). Bioavailability of catechins from ready-to-drink tea. Nutrition (Burbank, Los Angeles County, Calif.), 26(5), 528-33. https://doi.org/10.1016/j.nut.2009.06.013
Del Rio D, et al. Bioavailability of Catechins From Ready-to-drink Tea. Nutrition. 2010;26(5):528-33. PubMed PMID: 19765952.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bioavailability of catechins from ready-to-drink tea. AU - Del Rio,Daniele, AU - Calani,Luca, AU - Scazzina,Francesca, AU - Jechiu,Lucia, AU - Cordero,Chiara, AU - Brighenti,Furio, Y1 - 2009/09/17/ PY - 2009/05/11/received PY - 2009/06/13/accepted PY - 2009/9/22/entrez PY - 2009/9/22/pubmed PY - 2010/6/29/medline SP - 528 EP - 33 JF - Nutrition (Burbank, Los Angeles County, Calif.) JO - Nutrition VL - 26 IS - 5 N2 - OBJECTIVE: Because consumption of teas may be associated with potential health benefits due to its content in polyphenols and in Western countries the consumption of tea is equally divided between the hot and the ready-to-drink (RTD) cold versions of this typical beverage, the aim of this work was to study the absorption and metabolism of flavan-3-ols in human volunteers after the ingestion of a commercial RTD tea. METHODS: A feeding study was carried out in 20 healthy human volunteers and urine samples were collected for 24h after tea ingestion. Flavan-3-ols-derived molecules were identified and quantified in urine samples by high-performance liquid chromatography with tandem mass spectrometric detection. RESULTS: Eight relevant metabolites were identified in urine, all modified flavan-3-ols with the exception of unmetabolized gallic acid. The urinary excretion of flavan-3-ols was equal to 7.2% of the intake with tea. Gallic acid, which was abundant in the RTD tea used in this study, reached a 4.5% of the drunken amount. CONCLUSIONS: The bioavailability values observed are in agreement with previous reports, although the dosage of polyphenols ingested in this study is remarkably lower. Moreover, the use of a group of 20 volunteers, more than the average number of subjects used for usual human acute-feeding studies involving polyphenols, provides additional credibility to the results. After drinking the RTD ice tea used in this study, the internal compartments are exposed to non-marginal doses of flavanols and flavanol metabolites up to 24h. SN - 1873-1244 UR - https://www.unboundmedicine.com/medline/citation/19765952/Bioavailability_of_catechins_from_ready_to_drink_tea_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0899-9007(09)00259-7 DB - PRIME DP - Unbound Medicine ER -