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Family context and duration of untreated psychosis (DUP): results from the Sao Paulo Study.
Schizophr Res. 2010 Jun; 119(1-3):124-30.SR

Abstract

BACKGROUND

Duration of untreated psychosis (DUP) depends on several factors, including socio-demographic, socioeconomic, clinical and contextual circumstances, such as availability of mental health services. Living arrangements may also play a role, especially in low- and middle-income countries, where most people who develop psychosis live with their relatives.

METHODS

Population-based study of first-episode psychosis in São Paulo, Brazil. Participants were aged 18-64 years, lived in a defined geographic area of the city and had a first contact in life with mental health services due to a psychotic episode. Duration of untreated psychosis was defined as the period between onset of first psychotic symptom and first contact with health service due to psychosis. The median DUP was used to classify participants into short and long DUP. Psychopathology, social adjustment and psychiatric diagnoses were made with standardized assessments. Type of service sought and living arrangements were examined.

RESULTS

Two hundred participants were included (52% women, 61% non-affective psychoses). The median DUP was 4.1 weeks (inter-quartile range: 1.9-11.4), and was shorter for affective psychoses. Most participants had their first contact with psychiatric emergency services. Those who did not live with a relative (children older than 18 years, parents, partner) were more likely to present long DUP (OR: 2.63; 95%CI: 0.98-7.04); p=0.05).

CONCLUSION

The DUP in São Paulo was shorter than expected. Living arrangements may play an important role in shortening the DUP in urban centres of low- and middle income countries that have a network of mental health services.

Authors+Show Affiliations

Department of Psychiatry, Faculty of Medicine, University of São Paulo, Rua Ovídio Pires de Campos 785, CEP 05403-010, São Paulo, SP, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19767177

Citation

Oliveira, Alexandra M., et al. "Family Context and Duration of Untreated Psychosis (DUP): Results From the Sao Paulo Study." Schizophrenia Research, vol. 119, no. 1-3, 2010, pp. 124-30.
Oliveira AM, Menezes PR, Busatto GF, et al. Family context and duration of untreated psychosis (DUP): results from the Sao Paulo Study. Schizophr Res. 2010;119(1-3):124-30.
Oliveira, A. M., Menezes, P. R., Busatto, G. F., McGuire, P. K., Murray, R. M., & Scazufca, M. (2010). Family context and duration of untreated psychosis (DUP): results from the Sao Paulo Study. Schizophrenia Research, 119(1-3), 124-30. https://doi.org/10.1016/j.schres.2009.08.018
Oliveira AM, et al. Family Context and Duration of Untreated Psychosis (DUP): Results From the Sao Paulo Study. Schizophr Res. 2010;119(1-3):124-30. PubMed PMID: 19767177.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Family context and duration of untreated psychosis (DUP): results from the Sao Paulo Study. AU - Oliveira,Alexandra M, AU - Menezes,Paulo R, AU - Busatto,Geraldo F, AU - McGuire,Philip K, AU - Murray,Robin M, AU - Scazufca,Marcia, Y1 - 2009/09/20/ PY - 2009/05/05/received PY - 2009/08/27/revised PY - 2009/08/27/accepted PY - 2009/9/22/entrez PY - 2009/9/22/pubmed PY - 2010/7/31/medline SP - 124 EP - 30 JF - Schizophrenia research JO - Schizophr Res VL - 119 IS - 1-3 N2 - BACKGROUND: Duration of untreated psychosis (DUP) depends on several factors, including socio-demographic, socioeconomic, clinical and contextual circumstances, such as availability of mental health services. Living arrangements may also play a role, especially in low- and middle-income countries, where most people who develop psychosis live with their relatives. METHODS: Population-based study of first-episode psychosis in São Paulo, Brazil. Participants were aged 18-64 years, lived in a defined geographic area of the city and had a first contact in life with mental health services due to a psychotic episode. Duration of untreated psychosis was defined as the period between onset of first psychotic symptom and first contact with health service due to psychosis. The median DUP was used to classify participants into short and long DUP. Psychopathology, social adjustment and psychiatric diagnoses were made with standardized assessments. Type of service sought and living arrangements were examined. RESULTS: Two hundred participants were included (52% women, 61% non-affective psychoses). The median DUP was 4.1 weeks (inter-quartile range: 1.9-11.4), and was shorter for affective psychoses. Most participants had their first contact with psychiatric emergency services. Those who did not live with a relative (children older than 18 years, parents, partner) were more likely to present long DUP (OR: 2.63; 95%CI: 0.98-7.04); p=0.05). CONCLUSION: The DUP in São Paulo was shorter than expected. Living arrangements may play an important role in shortening the DUP in urban centres of low- and middle income countries that have a network of mental health services. SN - 1573-2509 UR - https://www.unboundmedicine.com/medline/citation/19767177/Family_context_and_duration_of_untreated_psychosis__DUP_:_results_from_the_Sao_Paulo_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0920-9964(09)00418-6 DB - PRIME DP - Unbound Medicine ER -