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Chemical composition and antibacterial activity of the essential oil of Cordia verbenacea from the Venezuelan Andes.
Nat Prod Commun. 2009 Aug; 4(8):1119-22.NP

Abstract

The essential oil of Cordia verbenacea D.C. (Boraginaceae) that grows in Mérida-Venezuela was obtained by hydrodistillation from the aerial parts of the plant, yielding 0.21%. The oil was analyzed by GC-FID and GC-MS. Thirty one components which made up 94.3% of the oil were identified. The most abundant constituents found were: tricyclene (23.9%), bicyclogermacrene (11.7%), germacrene D (9.9%) and beta-caryophyllene (8.2%). Antibacterial activity determination was carried out according to the disc diffusion assay. Activity against Gram-positive bacteria Staphylococcus aureus ATCC 6538 and Enterococcus faecalis ATCC 29212, at a minimal inhibitory concentration (MIC) of 170 microg/mL and 200 microg/mL, was found.

Authors+Show Affiliations

Research Institute, Faculty of Pharmacy and Bioanalysis, University of Los Andes, Mérida, Venezuela. gmeccia@ula.veNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19768996

Citation

Meccia, Gina, et al. "Chemical Composition and Antibacterial Activity of the Essential Oil of Cordia Verbenacea From the Venezuelan Andes." Natural Product Communications, vol. 4, no. 8, 2009, pp. 1119-22.
Meccia G, Rojas LB, Velasco J, et al. Chemical composition and antibacterial activity of the essential oil of Cordia verbenacea from the Venezuelan Andes. Nat Prod Commun. 2009;4(8):1119-22.
Meccia, G., Rojas, L. B., Velasco, J., Díaz, T., Usubillaga, A., Arzola, J. C., & Ramos, S. (2009). Chemical composition and antibacterial activity of the essential oil of Cordia verbenacea from the Venezuelan Andes. Natural Product Communications, 4(8), 1119-22.
Meccia G, et al. Chemical Composition and Antibacterial Activity of the Essential Oil of Cordia Verbenacea From the Venezuelan Andes. Nat Prod Commun. 2009;4(8):1119-22. PubMed PMID: 19768996.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antibacterial activity of the essential oil of Cordia verbenacea from the Venezuelan Andes. AU - Meccia,Gina, AU - Rojas,Luis B, AU - Velasco,Judith, AU - Díaz,Tulia, AU - Usubillaga,Alfredo, AU - Arzola,Juan Carmona, AU - Ramos,Sulymar, PY - 2009/9/23/entrez PY - 2009/9/23/pubmed PY - 2010/1/7/medline SP - 1119 EP - 22 JF - Natural product communications JO - Nat Prod Commun VL - 4 IS - 8 N2 - The essential oil of Cordia verbenacea D.C. (Boraginaceae) that grows in Mérida-Venezuela was obtained by hydrodistillation from the aerial parts of the plant, yielding 0.21%. The oil was analyzed by GC-FID and GC-MS. Thirty one components which made up 94.3% of the oil were identified. The most abundant constituents found were: tricyclene (23.9%), bicyclogermacrene (11.7%), germacrene D (9.9%) and beta-caryophyllene (8.2%). Antibacterial activity determination was carried out according to the disc diffusion assay. Activity against Gram-positive bacteria Staphylococcus aureus ATCC 6538 and Enterococcus faecalis ATCC 29212, at a minimal inhibitory concentration (MIC) of 170 microg/mL and 200 microg/mL, was found. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/19768996/Chemical_composition_and_antibacterial_activity_of_the_essential_oil_of_Cordia_verbenacea_from_the_Venezuelan_Andes_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -