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Anti-Helicobacter pylori activity and essential oil composition of Thymus caramanicus from Iran.
Nat Prod Commun. 2009 Aug; 4(8):1139-42.NP

Abstract

The essential oil of the dried aerial parts of Thymus caramanicus at full flowering stage was prepared by hydrodistillation with a yield of 2.5% oil. The oil analysis by a combination of capillary GC and GC-MS revealed 26 components of which carvacrol (68.9%) was the main component, followed by p-cymene (6.0%), thymol (5.3%), gamma-terpinene (4.6%) and borneol (4.0%) representing 98.9% of the total oil. The in vitro antibacterial activity of the essential oil was determined against ten clinical isolates of Helicobacter pylori using disc diffusion, as well as measurement of minimum inhibitory concentrations. The results showed high inhibitory activity against all test bacteria by the disc diffusion method (zones of inhibition of 50.0 - 65.0 mm). Minimum inhibitory concentration values were within the range 14.5 - 58.0 microg/mL for the clinical isolates.

Authors+Show Affiliations

Eftekhar F
Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University GC, Evin, Tehran, Iran. f-eftekhar@cc.sbu.ac.ir
Nariman F
No affiliation info available
Yousefzadi M
No affiliation info available
Hadiand J
No affiliation info available
Ebrahimi SN
No affiliation info available

MeSH

Anti-Bacterial AgentsCamphanesChromatography, GasCyclohexane MonoterpenesCymenesGas Chromatography-Mass SpectrometryHelicobacter pyloriMicrobial Sensitivity TestsMonoterpenesOils, VolatilePlant OilsThymolThymus Plant

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19769000

Citation

Eftekhar, Fereshteh, et al. "Anti-Helicobacter Pylori Activity and Essential Oil Composition of Thymus Caramanicus From Iran." Natural Product Communications, vol. 4, no. 8, 2009, pp. 1139-42.
Eftekhar F, Nariman F, Yousefzadi M, et al. Anti-Helicobacter pylori activity and essential oil composition of Thymus caramanicus from Iran. Nat Prod Commun. 2009;4(8):1139-42.
Eftekhar, F., Nariman, F., Yousefzadi, M., Hadiand, J., & Ebrahimi, S. N. (2009). Anti-Helicobacter pylori activity and essential oil composition of Thymus caramanicus from Iran. Natural Product Communications, 4(8), 1139-42.
Eftekhar F, et al. Anti-Helicobacter Pylori Activity and Essential Oil Composition of Thymus Caramanicus From Iran. Nat Prod Commun. 2009;4(8):1139-42. PubMed PMID: 19769000.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-Helicobacter pylori activity and essential oil composition of Thymus caramanicus from Iran. AU - Eftekhar,Fereshteh, AU - Nariman,Farahnaz, AU - Yousefzadi,Morteza, AU - Hadiand,Javad, AU - Ebrahimi,Samad Nejad, PY - 2009/9/23/entrez PY - 2009/9/23/pubmed PY - 2010/1/7/medline SP - 1139 EP - 42 JF - Natural product communications JO - Nat Prod Commun VL - 4 IS - 8 N2 - The essential oil of the dried aerial parts of Thymus caramanicus at full flowering stage was prepared by hydrodistillation with a yield of 2.5% oil. The oil analysis by a combination of capillary GC and GC-MS revealed 26 components of which carvacrol (68.9%) was the main component, followed by p-cymene (6.0%), thymol (5.3%), gamma-terpinene (4.6%) and borneol (4.0%) representing 98.9% of the total oil. The in vitro antibacterial activity of the essential oil was determined against ten clinical isolates of Helicobacter pylori using disc diffusion, as well as measurement of minimum inhibitory concentrations. The results showed high inhibitory activity against all test bacteria by the disc diffusion method (zones of inhibition of 50.0 - 65.0 mm). Minimum inhibitory concentration values were within the range 14.5 - 58.0 microg/mL for the clinical isolates. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/19769000/Anti_Helicobacter_pylori_activity_and_essential_oil_composition_of_Thymus_caramanicus_from_Iran_ DB - PRIME DP - Unbound Medicine ER -