Tags

Type your tag names separated by a space and hit enter

United airways: the impact of chronic rhinosinusitis and nasal polyps in bronchiectasic patient's quality of life.
Allergy. 2009 Oct; 64(10):1524-9.A

Abstract

BACKGROUND

The nose and the bronchi belong, in anatomical and physiopathological terms, to the concept of united airways. Associations between upper and lower airways diseases have been demonstrated in allergic rhinitis and asthma, nasal polyposis (NP) and asthma, chronic rhinosinusitis (CRS) and chronic obstructive pulmonary disease, and more recently CRS/NP and bronchiectasis (BQ).

OBJECTIVE

To evaluate the impact of CRS on quality of life (QoL) of patients with BQ, and to correlate these findings with the pulmonary status, nasal symptoms, and general health status.

METHODS

In a prospective study, patients with BQ (n = 80) were evaluated for CRS and NP using EP(3)OS criteria, and severity of BQ using chest high resolution computed tomography (HRCT)-scan. Quality of life was assessed in all patients by using specific [Sinonasal Outcome Test-20 (SNOT-20), St George Respiratory Questionnaire (SGRQ)], and generic (Short Form-36; SF-36) questionnaires.

RESULTS

Using SNOT-20, patients with CRS had worse QoL (2.1 +/- 0.1; P < 0.001) than patients without CRS (0.4 +/- 0.06). Using SGRQ total score, patients with CRS had worse QoL (43.7 +/- 2.2; P < 0.001) than patients without CRS (24.7 +/- 2.5). Using SF-36, patients with CRS had worse QoL, both in the physical summary (64 +/- 3.4; P < 0.05) and the mental summary (65.5 +/- 4.7; P < 0.05), than patients without CRS (physical summary [PS]: 76.2 +/- 3.3; mental summary [MS]: 78.3 +/- 5.3, respectively). Sinonasal Outcome Test-20 was correlated with SGRQ total score (r = 0.72; P < 0.01), and SF-36 physical summary (r = -0.63; P < 0.01). St George Respiratory Questionnaire was correlated with SF-36 on physical summary (r = -0.58; P < 0.05) and with forced expiratory volume in 1 s (r = -0.41; P < 0.05).

CONCLUSION

These results suggested that CRS, measured by both specific and generic questionnaires, has a considerable impact on the QoL of patients with BQ.

Authors+Show Affiliations

Rhinology Unit and Smell Clinic, Department of Otorhinolaryngology, Hospital Clínic i Universitari, Barcelona, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19772517

Citation

Guilemany, J M., et al. "United Airways: the Impact of Chronic Rhinosinusitis and Nasal Polyps in Bronchiectasic Patient's Quality of Life." Allergy, vol. 64, no. 10, 2009, pp. 1524-9.
Guilemany JM, Angrill J, Alobid I, et al. United airways: the impact of chronic rhinosinusitis and nasal polyps in bronchiectasic patient's quality of life. Allergy. 2009;64(10):1524-9.
Guilemany, J. M., Angrill, J., Alobid, I., Centellas, S., Prades, E., Roca, J., Pujols, L., Bernal-Sprekelsen, M., Picado, C., & Mullol, J. (2009). United airways: the impact of chronic rhinosinusitis and nasal polyps in bronchiectasic patient's quality of life. Allergy, 64(10), 1524-9. https://doi.org/10.1111/j.1398-9995.2009.02011.x
Guilemany JM, et al. United Airways: the Impact of Chronic Rhinosinusitis and Nasal Polyps in Bronchiectasic Patient's Quality of Life. Allergy. 2009;64(10):1524-9. PubMed PMID: 19772517.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - United airways: the impact of chronic rhinosinusitis and nasal polyps in bronchiectasic patient's quality of life. AU - Guilemany,J M, AU - Angrill,J, AU - Alobid,I, AU - Centellas,S, AU - Prades,E, AU - Roca,J, AU - Pujols,L, AU - Bernal-Sprekelsen,M, AU - Picado,C, AU - Mullol,J, PY - 2009/9/24/entrez PY - 2009/9/24/pubmed PY - 2010/1/7/medline SP - 1524 EP - 9 JF - Allergy JO - Allergy VL - 64 IS - 10 N2 - BACKGROUND: The nose and the bronchi belong, in anatomical and physiopathological terms, to the concept of united airways. Associations between upper and lower airways diseases have been demonstrated in allergic rhinitis and asthma, nasal polyposis (NP) and asthma, chronic rhinosinusitis (CRS) and chronic obstructive pulmonary disease, and more recently CRS/NP and bronchiectasis (BQ). OBJECTIVE: To evaluate the impact of CRS on quality of life (QoL) of patients with BQ, and to correlate these findings with the pulmonary status, nasal symptoms, and general health status. METHODS: In a prospective study, patients with BQ (n = 80) were evaluated for CRS and NP using EP(3)OS criteria, and severity of BQ using chest high resolution computed tomography (HRCT)-scan. Quality of life was assessed in all patients by using specific [Sinonasal Outcome Test-20 (SNOT-20), St George Respiratory Questionnaire (SGRQ)], and generic (Short Form-36; SF-36) questionnaires. RESULTS: Using SNOT-20, patients with CRS had worse QoL (2.1 +/- 0.1; P < 0.001) than patients without CRS (0.4 +/- 0.06). Using SGRQ total score, patients with CRS had worse QoL (43.7 +/- 2.2; P < 0.001) than patients without CRS (24.7 +/- 2.5). Using SF-36, patients with CRS had worse QoL, both in the physical summary (64 +/- 3.4; P < 0.05) and the mental summary (65.5 +/- 4.7; P < 0.05), than patients without CRS (physical summary [PS]: 76.2 +/- 3.3; mental summary [MS]: 78.3 +/- 5.3, respectively). Sinonasal Outcome Test-20 was correlated with SGRQ total score (r = 0.72; P < 0.01), and SF-36 physical summary (r = -0.63; P < 0.01). St George Respiratory Questionnaire was correlated with SF-36 on physical summary (r = -0.58; P < 0.05) and with forced expiratory volume in 1 s (r = -0.41; P < 0.05). CONCLUSION: These results suggested that CRS, measured by both specific and generic questionnaires, has a considerable impact on the QoL of patients with BQ. SN - 1398-9995 UR - https://www.unboundmedicine.com/medline/citation/19772517/United_airways:_the_impact_of_chronic_rhinosinusitis_and_nasal_polyps_in_bronchiectasic_patient's_quality_of_life_ L2 - https://doi.org/10.1111/j.1398-9995.2009.02011.x DB - PRIME DP - Unbound Medicine ER -