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Interaction between familial history of obesity and fat intakes on obesity phenotypes.
J Nutrigenet Nutrigenomics. 2009; 2(1):37-42.JN

Abstract

AIM

To evaluate whether familial history of obesity (FHO) interacts with dietary fat intake (DFI) on obesity-related phenotypes.

METHODS

We recruited 664 participants aged between 18 and 55 years. A positive FHO (FHO+) was defined as having at least 1 obese first-degree relative and a negative FHO (FHO-) as no obese first-degree relative. Dietary intakes were collected from a food-frequency questionnaire. Body mass index, weight and waist girth were recorded using standard procedures. Fat mass and fat-free mass were assessed by electrical bioimpedance.

RESULTS

Significant interaction effects (FHO x DFI) were observed for body mass index, weight, waist girth and fat mass (p interaction = 0.05, 0.04, 0.04, 0.02, respectively). Among FHO+ individuals, indices of obesity increased with an increasing amount of DFI, whereas these associations were not observed in FHO- individuals. We also found that FHO+ individuals consuming a high-fat diet were at higher risk of obesity than FHO- individuals consuming a low-fat diet (3.6, CI 2.1-6.2).

CONCLUSION

These results suggest a stronger relationship between DFI and obesity-related phenotypes in individuals with FHO+.

Authors+Show Affiliations

Department of Food Science and Nutrition, Laval University, Quebec City, Que., Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19776637

Citation

Paradis, Ann-Marie, et al. "Interaction Between Familial History of Obesity and Fat Intakes On Obesity Phenotypes." Journal of Nutrigenetics and Nutrigenomics, vol. 2, no. 1, 2009, pp. 37-42.
Paradis AM, Godin G, Pérusse L, et al. Interaction between familial history of obesity and fat intakes on obesity phenotypes. J Nutrigenet Nutrigenomics. 2009;2(1):37-42.
Paradis, A. M., Godin, G., Pérusse, L., & Vohl, M. C. (2009). Interaction between familial history of obesity and fat intakes on obesity phenotypes. Journal of Nutrigenetics and Nutrigenomics, 2(1), 37-42. https://doi.org/10.1159/000191281
Paradis AM, et al. Interaction Between Familial History of Obesity and Fat Intakes On Obesity Phenotypes. J Nutrigenet Nutrigenomics. 2009;2(1):37-42. PubMed PMID: 19776637.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Interaction between familial history of obesity and fat intakes on obesity phenotypes. AU - Paradis,Ann-Marie, AU - Godin,Gaston, AU - Pérusse,Louis, AU - Vohl,Marie-Claude, Y1 - 2009/01/16/ PY - 2008/06/16/received PY - 2008/10/21/accepted PY - 2009/9/25/entrez PY - 2009/9/25/pubmed PY - 2009/10/22/medline SP - 37 EP - 42 JF - Journal of nutrigenetics and nutrigenomics JO - J Nutrigenet Nutrigenomics VL - 2 IS - 1 N2 - AIM: To evaluate whether familial history of obesity (FHO) interacts with dietary fat intake (DFI) on obesity-related phenotypes. METHODS: We recruited 664 participants aged between 18 and 55 years. A positive FHO (FHO+) was defined as having at least 1 obese first-degree relative and a negative FHO (FHO-) as no obese first-degree relative. Dietary intakes were collected from a food-frequency questionnaire. Body mass index, weight and waist girth were recorded using standard procedures. Fat mass and fat-free mass were assessed by electrical bioimpedance. RESULTS: Significant interaction effects (FHO x DFI) were observed for body mass index, weight, waist girth and fat mass (p interaction = 0.05, 0.04, 0.04, 0.02, respectively). Among FHO+ individuals, indices of obesity increased with an increasing amount of DFI, whereas these associations were not observed in FHO- individuals. We also found that FHO+ individuals consuming a high-fat diet were at higher risk of obesity than FHO- individuals consuming a low-fat diet (3.6, CI 2.1-6.2). CONCLUSION: These results suggest a stronger relationship between DFI and obesity-related phenotypes in individuals with FHO+. SN - 1661-6499 UR - https://www.unboundmedicine.com/medline/citation/19776637/Interaction_between_familial_history_of_obesity_and_fat_intakes_on_obesity_phenotypes_ L2 - https://www.karger.com?DOI=10.1159/000191281 DB - PRIME DP - Unbound Medicine ER -