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[Early treatment of Parkinson's disease with levodopa].
Ned Tijdschr Geneeskd. 2009; 153:A286.NT

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder characterised by tremor, rigidity and bradykinesia. The current treatment, for example with levodopa or dopamine-agonists, is complicated by response fluctuations, dyskinesias and gastro-intestinal side-effects. These, and various other reasons including fear of levodopa toxicity, have led to reluctance in starting medical treatment in PD. Especially during the last decade it has become clear that there is no scientific substrate for this reluctance. The aim should be to minimize the restraints in daily activity caused by PD, where medications including levodopa and dopamine-agonists have proven to be effective.

Authors+Show Affiliations

Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Neurologie, Amsterdam, The Netherlands. v.j.odekerken@amc.uva.nlNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

dut

PubMed ID

19785822

Citation

Odekerken, Vincent J J., et al. "[Early Treatment of Parkinson's Disease With Levodopa]." Nederlands Tijdschrift Voor Geneeskunde, vol. 153, 2009, pp. A286.
Odekerken VJ, Post B, Verschuur CV, et al. [Early treatment of Parkinson's disease with levodopa]. Ned Tijdschr Geneeskd. 2009;153:A286.
Odekerken, V. J., Post, B., Verschuur, C. V., & de Bie, R. M. (2009). [Early treatment of Parkinson's disease with levodopa]. Nederlands Tijdschrift Voor Geneeskunde, 153, A286.
Odekerken VJ, et al. [Early Treatment of Parkinson's Disease With Levodopa]. Ned Tijdschr Geneeskd. 2009;153:A286. PubMed PMID: 19785822.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Early treatment of Parkinson's disease with levodopa]. AU - Odekerken,Vincent J J, AU - Post,Bart, AU - Verschuur,Constant V M, AU - de Bie,Rob M A, PY - 2009/9/30/entrez PY - 2009/9/30/pubmed PY - 2009/12/16/medline SP - A286 EP - A286 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 153 N2 - Parkinson's disease (PD) is a neurodegenerative disorder characterised by tremor, rigidity and bradykinesia. The current treatment, for example with levodopa or dopamine-agonists, is complicated by response fluctuations, dyskinesias and gastro-intestinal side-effects. These, and various other reasons including fear of levodopa toxicity, have led to reluctance in starting medical treatment in PD. Especially during the last decade it has become clear that there is no scientific substrate for this reluctance. The aim should be to minimize the restraints in daily activity caused by PD, where medications including levodopa and dopamine-agonists have proven to be effective. SN - 1876-8784 UR - https://www.unboundmedicine.com/medline/citation/19785822/[Early_treatment_of_Parkinson's_disease_with_levodopa]_ L2 - https://medlineplus.gov/parkinsonsdisease.html DB - PRIME DP - Unbound Medicine ER -