Multiple sclerosis. TNFRSF1A, TRAPS and multiple sclerosis.
A genome-wide association study has identified the R92Q variant of the TNFRSF1A gene as a new susceptibility locus for multiple sclerosis. This locus is of special interest because the R92Q substitution was previously detected in a group of multiple sclerosis patients who had additional symptoms compatible with the autoinflammatory syndrome TRAPS.
Institute of Clinical Neuroimmunology-Campus Grosshadern, Ludwig Maximilians University of Munich, Marchioninistrasse 15, Munich, Germany. email@example.com
Genetic Predisposition to Disease
Genome-Wide Association Study
Receptors, Tumor Necrosis Factor
Receptors, Tumor Necrosis Factor, Type I
Tumor Necrosis Factor-alpha
Pub Type(s)Journal Article
Research Support, Non-U.S. Gov't