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Relationship between age and serum lipids in malnourished and well-fed pre-school children in Zaria, Nigeria.
Niger J Clin Pract. 2009 Sep; 12(3):273-6.NJ

Abstract

OBJECTIVE

The objective of this study was to evaluate the relationship between age and serum total cholesterol (TC) and triglyceride (TG) in malnourished and well-fed pre-school Nigerian children in Zaria, northern Nigeria.

MATERIALS AND METHODS

Serum total cholesterol (TC) and TG concentrations were measured in 115 malnourished and 115 age- and gender-matched well-fed children aged one (1)-three (3) years. These consisted of 25, 30, 30 and 30 children with kwashiorkor, marasmic-kwashiorkor, marasmus and underweight, respectively with their corresponding age- and gender-matched well-fed children. There were 60 males and 55 females each of malnourished and well-fed children. Concentrations of TC and TG were measured by enzymatic colorimetric method using reagent kits supplied by HUMAN, Gesel Für Biochemical Und Diagnostica mbH (Wiesbaden, Germany).

RESULTS

There was no correlation between age and serum TC in malnourished children (r = 0.0101, p = 0.9250), while the correlation was negative and significant in well-fed children (r = 0.3599, p = 0.3110). Similarly, there was no correlation between age and serum TG in malnourished chidren (r = 0.0605, p = 0.4623) but negative and significant correlation in well-fed children (r = 0.3210, p = 0.0001).

CONCLUSION

The findings of this study demonstrate that in well-fed pre-school children, serum lipids decrease with advancing age and that this pattern was abolished in malnourished children. This contribution should be noted and considered when interpreting serum lipid results in children.

Authors+Show Affiliations

Department of Chemical Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. shehuakuyam@yahoo.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19803024

Citation

Akuyam, S A., et al. "Relationship Between Age and Serum Lipids in Malnourished and Well-fed Pre-school Children in Zaria, Nigeria." Nigerian Journal of Clinical Practice, vol. 12, no. 3, 2009, pp. 273-6.
Akuyam SA, Isah HS, Ogala WN. Relationship between age and serum lipids in malnourished and well-fed pre-school children in Zaria, Nigeria. Niger J Clin Pract. 2009;12(3):273-6.
Akuyam, S. A., Isah, H. S., & Ogala, W. N. (2009). Relationship between age and serum lipids in malnourished and well-fed pre-school children in Zaria, Nigeria. Nigerian Journal of Clinical Practice, 12(3), 273-6.
Akuyam SA, Isah HS, Ogala WN. Relationship Between Age and Serum Lipids in Malnourished and Well-fed Pre-school Children in Zaria, Nigeria. Niger J Clin Pract. 2009;12(3):273-6. PubMed PMID: 19803024.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between age and serum lipids in malnourished and well-fed pre-school children in Zaria, Nigeria. AU - Akuyam,S A, AU - Isah,H S, AU - Ogala,W N, PY - 2009/10/7/entrez PY - 2009/10/7/pubmed PY - 2009/11/7/medline SP - 273 EP - 6 JF - Nigerian journal of clinical practice JO - Niger J Clin Pract VL - 12 IS - 3 N2 - OBJECTIVE: The objective of this study was to evaluate the relationship between age and serum total cholesterol (TC) and triglyceride (TG) in malnourished and well-fed pre-school Nigerian children in Zaria, northern Nigeria. MATERIALS AND METHODS: Serum total cholesterol (TC) and TG concentrations were measured in 115 malnourished and 115 age- and gender-matched well-fed children aged one (1)-three (3) years. These consisted of 25, 30, 30 and 30 children with kwashiorkor, marasmic-kwashiorkor, marasmus and underweight, respectively with their corresponding age- and gender-matched well-fed children. There were 60 males and 55 females each of malnourished and well-fed children. Concentrations of TC and TG were measured by enzymatic colorimetric method using reagent kits supplied by HUMAN, Gesel Für Biochemical Und Diagnostica mbH (Wiesbaden, Germany). RESULTS: There was no correlation between age and serum TC in malnourished children (r = 0.0101, p = 0.9250), while the correlation was negative and significant in well-fed children (r = 0.3599, p = 0.3110). Similarly, there was no correlation between age and serum TG in malnourished chidren (r = 0.0605, p = 0.4623) but negative and significant correlation in well-fed children (r = 0.3210, p = 0.0001). CONCLUSION: The findings of this study demonstrate that in well-fed pre-school children, serum lipids decrease with advancing age and that this pattern was abolished in malnourished children. This contribution should be noted and considered when interpreting serum lipid results in children. SN - 1119-3077 UR - https://www.unboundmedicine.com/medline/citation/19803024/Relationship_between_age_and_serum_lipids_in_malnourished_and_well_fed_pre_school_children_in_Zaria_Nigeria_ L2 - https://medlineplus.gov/nutrition.html DB - PRIME DP - Unbound Medicine ER -