TY - JOUR T1 - [Cirrhotic cardiomyopathy]. AU - Seirafi,M, AU - Spahr,L, PY - 2009/10/7/entrez PY - 2009/10/7/pubmed PY - 2009/10/30/medline SP - 1725-6, 1728, 1730-1 JF - Revue medicale suisse JO - Rev Med Suisse VL - 5 IS - 215 N2 - Cirrhotic cardiomyopathy is defined as structural and functional cardiac abnormalities occurring in patients with cirrhosis, in the absence of any other associated cardiac disease. Its main clinical features include systolic and diastolic dysfunctions, and electrophysiological changes. Cirrhotic cardiomyopathy is generally clinically latent and is unmasked when the patient is exposed to major physiological stress or after some procedures, thus leading to an overt cardiac failure. Pathogenic mechanisms include impaired beta-adrenergic receptor signal transduction and increased activity of cardio-depressor pathways. A certain reversibility has been shown in the medium-long term after a liver transplantation. This article proposes to review the physiopathological mechanisms underlying these abnormalities, their clinical impacts, and the management options. SN - 1660-9379 UR - https://www.unboundmedicine.com/medline/citation/19803225/[Cirrhotic_cardiomyopathy]_ L2 - http://www.diseaseinfosearch.org/result/1090 DB - PRIME DP - Unbound Medicine ER -