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[Observation on effective characteristics of acupuncture combined with medicine on depression of different syndrome types].
Zhongguo Zhen Jiu. 2009 Sep; 29(9):699-702.ZZ

Abstract

OBJECTIVE

To evaluate and analyze the clinical therapeutic effect and characteristics of acupuncture combined with medicine on depression of different syndrome types.

METHODS

Eighty cases of depression were dividede into liver qi stagnation and spleen deficiency group (group A, 35 cases), deficiency of both heart and spleen group (group B, 21 cases) and yang deficiency of both spleen and kidney group (group C, 24 cases) according to the syndrome differentiation. They were all treated with acupuncture at Baihui (GV 20), Yintang (EX-HN 3), Sishen-cong (EX-HN 1), Neiguan (PC 6) etc. and oral administration of 5-HT selective serotonin reuptake inhibitors (SSRI) tablets. The Hamilton depression scale (HAMD) and self-made syndrome differentiation symptoms evaluation scale were adopted to evaluate the therapeutic effect.

RESULTS

After treatment of 4 weeks, the total effective rate of 91.4% in group A and of 90.5% in group B, both were superior to that of 87.5% in group C (P < 0.01,P<0. 05). There was a significant difference in comparison of HAMD scores between the group A and group C after treatment of 4 weeks (P < 0.05). The symptom scores of syndrome differentiation in all three groups were obviously decreased after 1 week, 2 weeks and 4 weeks treatment compared with those before treatment (all P < 0.001), the symptom scores of group C had significant differences compared with the group A and group B after treatment of 2 weeks (P < 0.01, P < 0.05). The reducing scores rate of the group A had singificant differences compared with the group B and the group C after treatment of 4 weeks (both P < 0.05).

CONCLUSION

Acupuncture combined with SSRI has better therapeutic effect on depression of liver qi stagnation and spleen deficiency type. The syndrome differentiation symptoms evaluation scale is more exact and sensitive to evaluate the clinical therapeutic effect of TCM treatment.

Authors+Show Affiliations

Laboratory of Integrated Acupuncture and Medicine, Nanjing University of TCM, Nanjing 210029, China. nj_drwang@163.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

19803234

Citation

Wang, Xin-jun, et al. "[Observation On Effective Characteristics of Acupuncture Combined With Medicine On Depression of Different Syndrome Types]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 29, no. 9, 2009, pp. 699-702.
Wang XJ, Wang LL, Qiao HF, et al. [Observation on effective characteristics of acupuncture combined with medicine on depression of different syndrome types]. Zhongguo Zhen Jiu. 2009;29(9):699-702.
Wang, X. J., Wang, L. L., Qiao, H. F., & Li, J. B. (2009). [Observation on effective characteristics of acupuncture combined with medicine on depression of different syndrome types]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 29(9), 699-702.
Wang XJ, et al. [Observation On Effective Characteristics of Acupuncture Combined With Medicine On Depression of Different Syndrome Types]. Zhongguo Zhen Jiu. 2009;29(9):699-702. PubMed PMID: 19803234.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Observation on effective characteristics of acupuncture combined with medicine on depression of different syndrome types]. AU - Wang,Xin-jun, AU - Wang,Ling-ling, AU - Qiao,Hui-fen, AU - Li,Jian-bing, PY - 2009/10/7/entrez PY - 2009/10/7/pubmed PY - 2009/10/23/medline SP - 699 EP - 702 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 29 IS - 9 N2 - OBJECTIVE: To evaluate and analyze the clinical therapeutic effect and characteristics of acupuncture combined with medicine on depression of different syndrome types. METHODS: Eighty cases of depression were dividede into liver qi stagnation and spleen deficiency group (group A, 35 cases), deficiency of both heart and spleen group (group B, 21 cases) and yang deficiency of both spleen and kidney group (group C, 24 cases) according to the syndrome differentiation. They were all treated with acupuncture at Baihui (GV 20), Yintang (EX-HN 3), Sishen-cong (EX-HN 1), Neiguan (PC 6) etc. and oral administration of 5-HT selective serotonin reuptake inhibitors (SSRI) tablets. The Hamilton depression scale (HAMD) and self-made syndrome differentiation symptoms evaluation scale were adopted to evaluate the therapeutic effect. RESULTS: After treatment of 4 weeks, the total effective rate of 91.4% in group A and of 90.5% in group B, both were superior to that of 87.5% in group C (P < 0.01,P<0. 05). There was a significant difference in comparison of HAMD scores between the group A and group C after treatment of 4 weeks (P < 0.05). The symptom scores of syndrome differentiation in all three groups were obviously decreased after 1 week, 2 weeks and 4 weeks treatment compared with those before treatment (all P < 0.001), the symptom scores of group C had significant differences compared with the group A and group B after treatment of 2 weeks (P < 0.01, P < 0.05). The reducing scores rate of the group A had singificant differences compared with the group B and the group C after treatment of 4 weeks (both P < 0.05). CONCLUSION: Acupuncture combined with SSRI has better therapeutic effect on depression of liver qi stagnation and spleen deficiency type. The syndrome differentiation symptoms evaluation scale is more exact and sensitive to evaluate the clinical therapeutic effect of TCM treatment. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/19803234/[Observation_on_effective_characteristics_of_acupuncture_combined_with_medicine_on_depression_of_different_syndrome_types]_ L2 - http://www.diseaseinfosearch.org/result/2199 DB - PRIME DP - Unbound Medicine ER -