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[Role of surgery in the therapy of peptic ulcer after arrival of H2-blocking drugs].
G Chir. 1990 Sep; 11(9):466-70.GC

Abstract

This retrospective study was undertaken to determine if the advent of H2-blockers has altered the surgical treatment and the outcome of patients with peptic ulcer disease. The records of patients undergoing surgery for peptic ulcer disease at Montecchio Maggiore Hospital, Vicenza (Italy), from 1968 to 1977 (group A) and from 1979 to 1989 (group B) were reviewed. Data recorded included, ulcer location, surgical procedures (emergency or elective), indications for emergency surgery (perforation, bleeding). Statistical analysis was performed by means of the chi-square test. From 1968 to 1989, 15.810 surgical operations were performed: the indication was peptic ulcer disease in 398 cases (2.51%). The percentage of surgical operations performed for peptic ulcer was 3.54% in group A and 1.55% in group B. A marked decline in surgery for peptic ulcer was noted in group B, concerning both elective and emergency surgery; surgical interventions strongly decreased for both duodenal and gastric ulcer. This study demonstrates that H2-blockers have definitely altered the surgical treatment for peptic ulcer disease.

Authors+Show Affiliations

Divisione di Chirurgia Generale, Ospedale Civile di Montecchio Maggiore (VI).No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ita

PubMed ID

1981139

Citation

Perri, S, et al. "[Role of Surgery in the Therapy of Peptic Ulcer After Arrival of H2-blocking Drugs]." Il Giornale Di Chirurgia, vol. 11, no. 9, 1990, pp. 466-70.
Perri S, Amendolara M, Breda E, et al. [Role of surgery in the therapy of peptic ulcer after arrival of H2-blocking drugs]. G Chir. 1990;11(9):466-70.
Perri, S., Amendolara, M., Breda, E., Todarello, V., Gallo, G., Pietrangeli, F., Meneghini, G., & Gelmi, G. F. (1990). [Role of surgery in the therapy of peptic ulcer after arrival of H2-blocking drugs]. Il Giornale Di Chirurgia, 11(9), 466-70.
Perri S, et al. [Role of Surgery in the Therapy of Peptic Ulcer After Arrival of H2-blocking Drugs]. G Chir. 1990;11(9):466-70. PubMed PMID: 1981139.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Role of surgery in the therapy of peptic ulcer after arrival of H2-blocking drugs]. AU - Perri,S, AU - Amendolara,M, AU - Breda,E, AU - Todarello,V, AU - Gallo,G, AU - Pietrangeli,F, AU - Meneghini,G, AU - Gelmi,G F, PY - 1990/9/1/pubmed PY - 1990/9/1/medline PY - 1990/9/1/entrez SP - 466 EP - 70 JF - Il Giornale di chirurgia JO - G Chir VL - 11 IS - 9 N2 - This retrospective study was undertaken to determine if the advent of H2-blockers has altered the surgical treatment and the outcome of patients with peptic ulcer disease. The records of patients undergoing surgery for peptic ulcer disease at Montecchio Maggiore Hospital, Vicenza (Italy), from 1968 to 1977 (group A) and from 1979 to 1989 (group B) were reviewed. Data recorded included, ulcer location, surgical procedures (emergency or elective), indications for emergency surgery (perforation, bleeding). Statistical analysis was performed by means of the chi-square test. From 1968 to 1989, 15.810 surgical operations were performed: the indication was peptic ulcer disease in 398 cases (2.51%). The percentage of surgical operations performed for peptic ulcer was 3.54% in group A and 1.55% in group B. A marked decline in surgery for peptic ulcer was noted in group B, concerning both elective and emergency surgery; surgical interventions strongly decreased for both duodenal and gastric ulcer. This study demonstrates that H2-blockers have definitely altered the surgical treatment for peptic ulcer disease. SN - 0391-9005 UR - https://www.unboundmedicine.com/medline/citation/1981139/[Role_of_surgery_in_the_therapy_of_peptic_ulcer_after_arrival_of_H2_blocking_drugs]_ DB - PRIME DP - Unbound Medicine ER -