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Assessing acid-base disorders.

Abstract

Effective management of acid-base disorders depends on accurate diagnosis. Three distinct approaches are currently used in assessing acid-base disorders: the physiological approach, the base-excess approach, and the physicochemical approach. There are considerable differences among the three approaches. In this review, we first describe the conceptual framework of each approach, and comment on its attributes and drawbacks. We then highlight the application of each approach to patient care. We conclude with a brief synthesis and our recommendations for choosing an approach.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Medicine, Baylor College of Medicine, Houston, TX, USA.

    , ,

    Source

    Kidney international 76:12 2009 Dec pg 1239-47

    MeSH

    Acid-Base Equilibrium
    Acid-Base Imbalance
    Adult
    Female
    Humans
    Male
    Middle Aged
    Models, Biological

    Pub Type(s)

    Case Reports
    Comparative Study
    Journal Article
    Review

    Language

    eng

    PubMed ID

    19812535

    Citation

    TY - JOUR T1 - Assessing acid-base disorders. AU - Adrogué,Horacio J, AU - Gennari,F John, AU - Galla,John H, AU - Madias,Nicolaos E, Y1 - 2009/10/07/ PY - 2009/10/07/aheadofprint PY - 2009/10/9/entrez PY - 2009/10/9/pubmed PY - 2010/2/23/medline SP - 1239 EP - 47 JF - Kidney international JO - Kidney Int. VL - 76 IS - 12 N2 - Effective management of acid-base disorders depends on accurate diagnosis. Three distinct approaches are currently used in assessing acid-base disorders: the physiological approach, the base-excess approach, and the physicochemical approach. There are considerable differences among the three approaches. In this review, we first describe the conceptual framework of each approach, and comment on its attributes and drawbacks. We then highlight the application of each approach to patient care. We conclude with a brief synthesis and our recommendations for choosing an approach. SN - 1523-1755 UR - https://www.unboundmedicine.com/medline/citation/19812535/abstract/Assessing_acid_base_disorders_ L2 - http://dx.doi.org/10.1038/ki.2009.359 ER -