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Effects of acacia honey on wound healing in various rat models.
Phytother Res 2010; 24(4):583-6PR

Abstract

Honey is a traditional remedy for the treatment of infected wounds, and is becoming more important as microbial resistance to conventional therapeutic agents increases. A study was conducted to assess the wound-healing activity of Acacia honey using incision, excision, burn and dead-space wound models in rats. Different formulations of honey were used and rats were treated topically as well as orally. Both the higher and lower doses of honey produced a significant effect on healing (p < 0.05). The area of epithelization was found to increase, followed by an increase in wound contraction, skin-breaking strength, tissue granulation. The hydroxyproline content also increased in the rats treated with higher doses of honey compared to control, indicating an increase in collagen formation.

Authors+Show Affiliations

Department of Honey Bee Research, National Agricultural Research Council, PO NARC, Park Road, Islamabad, Pakistan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19813239

Citation

Iftikhar, F, et al. "Effects of Acacia Honey On Wound Healing in Various Rat Models." Phytotherapy Research : PTR, vol. 24, no. 4, 2010, pp. 583-6.
Iftikhar F, Arshad M, Rasheed F, et al. Effects of acacia honey on wound healing in various rat models. Phytother Res. 2010;24(4):583-6.
Iftikhar, F., Arshad, M., Rasheed, F., Amraiz, D., Anwar, P., & Gulfraz, M. (2010). Effects of acacia honey on wound healing in various rat models. Phytotherapy Research : PTR, 24(4), pp. 583-6. doi:10.1002/ptr.2990.
Iftikhar F, et al. Effects of Acacia Honey On Wound Healing in Various Rat Models. Phytother Res. 2010;24(4):583-6. PubMed PMID: 19813239.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of acacia honey on wound healing in various rat models. AU - Iftikhar,F, AU - Arshad,M, AU - Rasheed,F, AU - Amraiz,D, AU - Anwar,P, AU - Gulfraz,M, PY - 2009/10/9/entrez PY - 2009/10/9/pubmed PY - 2010/6/29/medline SP - 583 EP - 6 JF - Phytotherapy research : PTR JO - Phytother Res VL - 24 IS - 4 N2 - Honey is a traditional remedy for the treatment of infected wounds, and is becoming more important as microbial resistance to conventional therapeutic agents increases. A study was conducted to assess the wound-healing activity of Acacia honey using incision, excision, burn and dead-space wound models in rats. Different formulations of honey were used and rats were treated topically as well as orally. Both the higher and lower doses of honey produced a significant effect on healing (p < 0.05). The area of epithelization was found to increase, followed by an increase in wound contraction, skin-breaking strength, tissue granulation. The hydroxyproline content also increased in the rats treated with higher doses of honey compared to control, indicating an increase in collagen formation. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/19813239/Effects_of_acacia_honey_on_wound_healing_in_various_rat_models_ L2 - https://doi.org/10.1002/ptr.2990 DB - PRIME DP - Unbound Medicine ER -