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Inappropriate secretion of antidiuretic hormone: a rare complication after common bile duct exploration.
Hepatobiliary Pancreat Dis Int. 2009 Oct; 8(5):544-6.HP

Abstract

BACKGROUND

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) as a dilutional hyponatremia is due to a pathological increase of antidiuretic hormone (ADH). It is characterized by hyponatremia and decreased serum osmolarity as well as an increase in urinary osmolarity. The most common etiological factors of this syndrome include diseases or trauma of the central nervous system and malignant tumor or inflammation of the lung. SIADH following abdominal surgery is rare.

METHODS

We report the case of a 68-year-old woman who developed, 24 hours after common bile duct exploration and stone removal, continuous hyponatremia for 20 days and clinical manifestations of nausea, vomiting, and lethargy without focal neurological signs.

RESULT

Laboratory examinations supported the diagnosis of SIADH. After therapy with fluid restriction, the patient recovered.

CONCLUSION

There are diverse causes for SIADH. It is important to have kept this clinical possibility in mind in the differential diagnosis of refractory hyponatremia under any circumstances.

Authors+Show Affiliations

Department of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China. ruanyu525@163.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19822501

Citation

Ruan, Yu, et al. "Inappropriate Secretion of Antidiuretic Hormone: a Rare Complication After Common Bile Duct Exploration." Hepatobiliary & Pancreatic Diseases International : HBPD INT, vol. 8, no. 5, 2009, pp. 544-6.
Ruan Y, Zhang W, Wang QQ. Inappropriate secretion of antidiuretic hormone: a rare complication after common bile duct exploration. HBPD INT. 2009;8(5):544-6.
Ruan, Y., Zhang, W., & Wang, Q. Q. (2009). Inappropriate secretion of antidiuretic hormone: a rare complication after common bile duct exploration. Hepatobiliary & Pancreatic Diseases International : HBPD INT, 8(5), 544-6.
Ruan Y, Zhang W, Wang QQ. Inappropriate Secretion of Antidiuretic Hormone: a Rare Complication After Common Bile Duct Exploration. HBPD INT. 2009;8(5):544-6. PubMed PMID: 19822501.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Inappropriate secretion of antidiuretic hormone: a rare complication after common bile duct exploration. AU - Ruan,Yu, AU - Zhang,Wei, AU - Wang,Qing-Qing, PY - 2009/10/14/entrez PY - 2009/10/14/pubmed PY - 2010/3/2/medline SP - 544 EP - 6 JF - Hepatobiliary & pancreatic diseases international : HBPD INT JO - HBPD INT VL - 8 IS - 5 N2 - BACKGROUND: The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) as a dilutional hyponatremia is due to a pathological increase of antidiuretic hormone (ADH). It is characterized by hyponatremia and decreased serum osmolarity as well as an increase in urinary osmolarity. The most common etiological factors of this syndrome include diseases or trauma of the central nervous system and malignant tumor or inflammation of the lung. SIADH following abdominal surgery is rare. METHODS: We report the case of a 68-year-old woman who developed, 24 hours after common bile duct exploration and stone removal, continuous hyponatremia for 20 days and clinical manifestations of nausea, vomiting, and lethargy without focal neurological signs. RESULT: Laboratory examinations supported the diagnosis of SIADH. After therapy with fluid restriction, the patient recovered. CONCLUSION: There are diverse causes for SIADH. It is important to have kept this clinical possibility in mind in the differential diagnosis of refractory hyponatremia under any circumstances. SN - 1499-3872 UR - https://www.unboundmedicine.com/medline/citation/19822501/Inappropriate_secretion_of_antidiuretic_hormone:_a_rare_complication_after_common_bile_duct_exploration_ DB - PRIME DP - Unbound Medicine ER -