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[Biological function of some elements and their compounds. I. Oxygen--the element of life and death].
Pol Merkur Lekarski. 2009 Sep; 27(159):245-8.PM

Abstract

Oxygen in cells occurs with carbon and hydrogen in most organic compounds that have either structural or metabolic functions. Atomic and molecular oxygen in singlet form or as free radicals (i.e., superoxide anionic radical, hydroxide radical) and as hydrogen peroxide, peroxidenitrate (III), nitrogen oxide are harmful to cellular structure and its metabolism and induce harmful genic mutations. Oxygen reactive species are secondary signaling molecules for transcription factors and cytokines. Therefore, it is crucial to maintain homeostasis at the level of reaction of oxidation and reduction. It is important for such significant biological processes as DNA synthesis, enzymes activation, cellular cycle regulation, gene transcription activation, and apoptosis. The review is also devoted for oxygen carriers in living organisms, e.g., hemoglobin, mioglobin and the toxicity of oxygen and ozone.

Authors+Show Affiliations

Higher School of Cosmetology and Protection of Health, Department of Chemistry Sciences, Bialystok, Poland.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

pol

PubMed ID

19827741

Citation

Puzanowska-Tarasiewicz, Helena, et al. "[Biological Function of some Elements and Their Compounds. I. Oxygen--the Element of Life and Death]." Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, vol. 27, no. 159, 2009, pp. 245-8.
Puzanowska-Tarasiewicz H, Kuźmicka L, Tarasiewicz M. [Biological function of some elements and their compounds. I. Oxygen--the element of life and death]. Pol Merkur Lekarski. 2009;27(159):245-8.
Puzanowska-Tarasiewicz, H., Kuźmicka, L., & Tarasiewicz, M. (2009). [Biological function of some elements and their compounds. I. Oxygen--the element of life and death]. Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego, 27(159), 245-8.
Puzanowska-Tarasiewicz H, Kuźmicka L, Tarasiewicz M. [Biological Function of some Elements and Their Compounds. I. Oxygen--the Element of Life and Death]. Pol Merkur Lekarski. 2009;27(159):245-8. PubMed PMID: 19827741.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Biological function of some elements and their compounds. I. Oxygen--the element of life and death]. AU - Puzanowska-Tarasiewicz,Helena, AU - Kuźmicka,Ludmila, AU - Tarasiewicz,Mirosław, PY - 2009/10/16/entrez PY - 2009/10/16/pubmed PY - 2009/11/18/medline SP - 245 EP - 8 JF - Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego JO - Pol Merkur Lekarski VL - 27 IS - 159 N2 - Oxygen in cells occurs with carbon and hydrogen in most organic compounds that have either structural or metabolic functions. Atomic and molecular oxygen in singlet form or as free radicals (i.e., superoxide anionic radical, hydroxide radical) and as hydrogen peroxide, peroxidenitrate (III), nitrogen oxide are harmful to cellular structure and its metabolism and induce harmful genic mutations. Oxygen reactive species are secondary signaling molecules for transcription factors and cytokines. Therefore, it is crucial to maintain homeostasis at the level of reaction of oxidation and reduction. It is important for such significant biological processes as DNA synthesis, enzymes activation, cellular cycle regulation, gene transcription activation, and apoptosis. The review is also devoted for oxygen carriers in living organisms, e.g., hemoglobin, mioglobin and the toxicity of oxygen and ozone. SN - 1426-9686 UR - https://www.unboundmedicine.com/medline/citation/19827741/[Biological_function_of_some_elements_and_their_compounds__I__Oxygen__the_element_of_life_and_death]_ DB - PRIME DP - Unbound Medicine ER -