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Analysis of antioxidants in insulation cladding of copper wire: a comparison of different mass spectrometric techniques (ESI-IT, MALDI-RTOF and RTOF-SIMS).
J Mass Spectrom. 2009 Dec; 44(12):1724-32.JM

Abstract

Commercial copper wire and its polymer insulation cladding was investigated for the presence of three synthetic antioxidants (ADK STAB AO412S, Irganox 1010 and Irganox MD 1024) by three different mass spectrometric techniques including electrospray ionization-ion trap-mass spectrometry (ESI-IT-MS), matrix-assisted laser desorption/ionization reflectron time-of-flight (TOF) mass spectrometry (MALDI-RTOF-MS) and reflectron TOF secondary ion mass spectrometry (RTOF-SIMS). The samples were analyzed either directly without any treatment (RTOF-SIMS) or after a simple liquid/liquid extraction step (ESI-IT-MS, MALDI-RTOF-MS and RTOF-SIMS). Direct analysis of the copper wire itself or of the insulation cladding by RTOF-SIMS allowed the detection of at least two of the three antioxidants but at rather low sensitivity as molecular radical cations and with fairly strong fragmentation (due to the highly energetic ion beam of the primary ion gun). ESI-IT- and MALDI-RTOF-MS-generated abundant protonated and/or cationized molecules (ammoniated or sodiated) from the liquid/liquid extract. Only ESI-IT-MS allowed simultaneous detection of all three analytes in the extract of insulation claddings. The latter two so-called 'soft' desorption/ionization techniques exhibited intense fragmentation only by applying low-energy collision-induced dissociation (CID) tandem MS on a multistage ion trap-instrument and high-energy CID on a tandem TOF-instrument (TOF/RTOF), respectively. Strong differences in the fragmentation behavior of the three analytes could be observed between the different CID spectra obtained from either the IT-instrument (collision energy in the very low eV range) or the TOF/RTOF-instrument (collision energy 20 keV), but both delivered important structural information.

Authors+Show Affiliations

Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19830787

Citation

Schnöller, Johannes, et al. "Analysis of Antioxidants in Insulation Cladding of Copper Wire: a Comparison of Different Mass Spectrometric Techniques (ESI-IT, MALDI-RTOF and RTOF-SIMS)." Journal of Mass Spectrometry : JMS, vol. 44, no. 12, 2009, pp. 1724-32.
Schnöller J, Pittenauer E, Hutter H, et al. Analysis of antioxidants in insulation cladding of copper wire: a comparison of different mass spectrometric techniques (ESI-IT, MALDI-RTOF and RTOF-SIMS). J Mass Spectrom. 2009;44(12):1724-32.
Schnöller, J., Pittenauer, E., Hutter, H., & Allmaier, G. (2009). Analysis of antioxidants in insulation cladding of copper wire: a comparison of different mass spectrometric techniques (ESI-IT, MALDI-RTOF and RTOF-SIMS). Journal of Mass Spectrometry : JMS, 44(12), 1724-32. https://doi.org/10.1002/jms.1681
Schnöller J, et al. Analysis of Antioxidants in Insulation Cladding of Copper Wire: a Comparison of Different Mass Spectrometric Techniques (ESI-IT, MALDI-RTOF and RTOF-SIMS). J Mass Spectrom. 2009;44(12):1724-32. PubMed PMID: 19830787.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of antioxidants in insulation cladding of copper wire: a comparison of different mass spectrometric techniques (ESI-IT, MALDI-RTOF and RTOF-SIMS). AU - Schnöller,Johannes, AU - Pittenauer,Ernst, AU - Hutter,Herbert, AU - Allmaier,Günter, PY - 2009/10/16/entrez PY - 2009/10/16/pubmed PY - 2009/10/16/medline SP - 1724 EP - 32 JF - Journal of mass spectrometry : JMS JO - J Mass Spectrom VL - 44 IS - 12 N2 - Commercial copper wire and its polymer insulation cladding was investigated for the presence of three synthetic antioxidants (ADK STAB AO412S, Irganox 1010 and Irganox MD 1024) by three different mass spectrometric techniques including electrospray ionization-ion trap-mass spectrometry (ESI-IT-MS), matrix-assisted laser desorption/ionization reflectron time-of-flight (TOF) mass spectrometry (MALDI-RTOF-MS) and reflectron TOF secondary ion mass spectrometry (RTOF-SIMS). The samples were analyzed either directly without any treatment (RTOF-SIMS) or after a simple liquid/liquid extraction step (ESI-IT-MS, MALDI-RTOF-MS and RTOF-SIMS). Direct analysis of the copper wire itself or of the insulation cladding by RTOF-SIMS allowed the detection of at least two of the three antioxidants but at rather low sensitivity as molecular radical cations and with fairly strong fragmentation (due to the highly energetic ion beam of the primary ion gun). ESI-IT- and MALDI-RTOF-MS-generated abundant protonated and/or cationized molecules (ammoniated or sodiated) from the liquid/liquid extract. Only ESI-IT-MS allowed simultaneous detection of all three analytes in the extract of insulation claddings. The latter two so-called 'soft' desorption/ionization techniques exhibited intense fragmentation only by applying low-energy collision-induced dissociation (CID) tandem MS on a multistage ion trap-instrument and high-energy CID on a tandem TOF-instrument (TOF/RTOF), respectively. Strong differences in the fragmentation behavior of the three analytes could be observed between the different CID spectra obtained from either the IT-instrument (collision energy in the very low eV range) or the TOF/RTOF-instrument (collision energy 20 keV), but both delivered important structural information. SN - 1096-9888 UR - https://www.unboundmedicine.com/medline/citation/19830787/Analysis_of_antioxidants_in_insulation_cladding_of_copper_wire:_a_comparison_of_different_mass_spectrometric_techniques__ESI_IT_MALDI_RTOF_and_RTOF_SIMS__ L2 - https://doi.org/10.1002/jms.1681 DB - PRIME DP - Unbound Medicine ER -
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