A multiresidue method for the determination of 118 pesticides in vegetable juice by gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry.J Agric Food Chem. 2009 Nov 11; 57(21):10095-101.JA
An analytical method has been developed for measuring 118 pesticides in vegetable juice. The extraction of pesticides was carried out based on dispersive solid-phase extraction, and determination was performed using gas chromatography with mass spectrometric detection (GC-MS-SIM) and liquid chromatography electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS). Pesticides were confirmed by their retention time and their quantification and identification ions by GC-MS-SIM or multiple reaction monitoring of two fragment ions by LC/ESI-MS/MS, respectively. Spiking experiments from 10 to 120 microg/kg were carried out to determine the recovery, precision, and limit of quantification (LOQ) of the method. The overall recoveries of all pesticides were between 77 and 114% with relative standard deviations lower than 14%. The LOQ for most compounds was below 5 microg/kg. The proposed method was applied successfully for the residue determination of the 118 pesticides in commercial vegetable juice samples.