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[Maggot therapy in wound management].
Tidsskr Nor Laegeforen. 2009 Sep 24; 129(18):1864-7.TN

Abstract

BACKGROUND

Maggots' ability to prevent infections and promote wound healing has been known since the 19th century. Increasing problems with treatment-resistant wounds and antibiotic-resistant bacteria has aroused interest in maggot therapy.

MATERIAL AND METHODS

Literature on maggot therapy - identified through a non-systematic search of Pubmed - was reviewed.

RESULTS

Maggot therapy is the medical use of disinfected fly larvae (usually the larvae of Lucilia sericata) in treatment of wounds resistant to conventional treatment. The maggots work through three mechanisms of action; they debride wounds by dissolving necrotic tissue, clean wounds by killing bacteria and promote wound healing. The larvae have a broad antibacterial action against Gram-negative and Gram-positive bacteria, including MRSA. Maggot therapy is used to debride a number of complicated skin and soft tissue wounds - e.g.. pressure ulcers, venous stasis ulcers, neurovascular ulcers, traumatic wounds and burns - but also as a treatment for osteomyelitis. Large controlled clinical trials have not been performed. Maggot therapy has not been associated with serious side effects.

INTERPRETATION

Maggot therapy seems to be an effective and environmentally friendly treatment of complicated necrotic wounds that are resistant to conventional treatment. Maggot therapy should also be considered in earlier stages of treatment.

Authors+Show Affiliations

Det medisinske fakultet, Universitetet i Tromsø, 9037 Tromsø, Norway. amniculus@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

nor

PubMed ID

19844278

Citation

Falch, Birgit Margrethe, et al. "[Maggot Therapy in Wound Management]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 129, no. 18, 2009, pp. 1864-7.
Falch BM, de Weerd L, Sundsfjord A. [Maggot therapy in wound management]. Tidsskr Nor Laegeforen. 2009;129(18):1864-7.
Falch, B. M., de Weerd, L., & Sundsfjord, A. (2009). [Maggot therapy in wound management]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 129(18), 1864-7. https://doi.org/10.4045/tidsskr.08.0656
Falch BM, de Weerd L, Sundsfjord A. [Maggot Therapy in Wound Management]. Tidsskr Nor Laegeforen. 2009 Sep 24;129(18):1864-7. PubMed PMID: 19844278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Maggot therapy in wound management]. AU - Falch,Birgit Margrethe, AU - de Weerd,Louis, AU - Sundsfjord,Arnfinn, PY - 2009/10/22/entrez PY - 2009/10/22/pubmed PY - 2009/10/29/medline SP - 1864 EP - 7 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr Nor Laegeforen VL - 129 IS - 18 N2 - BACKGROUND: Maggots' ability to prevent infections and promote wound healing has been known since the 19th century. Increasing problems with treatment-resistant wounds and antibiotic-resistant bacteria has aroused interest in maggot therapy. MATERIAL AND METHODS: Literature on maggot therapy - identified through a non-systematic search of Pubmed - was reviewed. RESULTS: Maggot therapy is the medical use of disinfected fly larvae (usually the larvae of Lucilia sericata) in treatment of wounds resistant to conventional treatment. The maggots work through three mechanisms of action; they debride wounds by dissolving necrotic tissue, clean wounds by killing bacteria and promote wound healing. The larvae have a broad antibacterial action against Gram-negative and Gram-positive bacteria, including MRSA. Maggot therapy is used to debride a number of complicated skin and soft tissue wounds - e.g.. pressure ulcers, venous stasis ulcers, neurovascular ulcers, traumatic wounds and burns - but also as a treatment for osteomyelitis. Large controlled clinical trials have not been performed. Maggot therapy has not been associated with serious side effects. INTERPRETATION: Maggot therapy seems to be an effective and environmentally friendly treatment of complicated necrotic wounds that are resistant to conventional treatment. Maggot therapy should also be considered in earlier stages of treatment. SN - 0807-7096 UR - https://www.unboundmedicine.com/medline/citation/19844278/[Maggot_therapy_in_wound_management]_ L2 - http://tidsskriftet.no/article/1893878 DB - PRIME DP - Unbound Medicine ER -