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Composition and anti-fungal activity of the essential oil from Cameroonian Vitex rivularis Gürke.
Nat Prod Res. 2009; 23(16):1478-84.NP

Abstract

The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of two populations of Vitex rivularis (subgenus Vitex) collected during the flowering phase of the plants was investigated by gas chromatography and gas chromatography/mass spectroscopy. Sesquiterpene hydrocarbons were the main group in both samples, the main compound being germacrene D. This composition is markedly different from that of the other African species, with the exception of Vitex ferruginea subsp. amboniensis, which belongs to the same subgenus as V. rivularis. Minimal inhibitory concentrations (MIC) and minimal lethal concentrations (MLC) were used to evaluate the anti-fungal activity against yeasts and dermatophyte strains. The oils exhibited significant anti-fungal activity against dermatophyte strains with MIC and MLC values ranging from 0.16 to 0.64 microL mL(-1) and 0.32 to 2.5 microL mL(-1), respectively. For some strains, MIC values were similar to MLC values, indicating the fungicidal activity of the oils. Nevertheless, these oils showed low activity against Candida spp. strains.

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Authors+Show Affiliations

Cabral C
Faculdade de Farmácia, Laboratório de Farmacognosia/CEF, Universidade de Coimbra, Coimbra, Portugal. cmdscabral@gmail.com
Gonçalves MJ
No affiliation info available
Cavaleiro C
No affiliation info available
Sales F
No affiliation info available
Boyom F
No affiliation info available
Salgueiro L
No affiliation info available

MeSH

Antifungal AgentsArthrodermataceaeAspergillusCandidaChromatography, GasCryptococcus neoformansFungiGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsOils, VolatileVitex

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19844822

Citation

Cabral, C, et al. "Composition and Anti-fungal Activity of the Essential Oil From Cameroonian Vitex Rivularis Gürke." Natural Product Research, vol. 23, no. 16, 2009, pp. 1478-84.
Cabral C, Gonçalves MJ, Cavaleiro C, et al. Composition and anti-fungal activity of the essential oil from Cameroonian Vitex rivularis Gürke. Nat Prod Res. 2009;23(16):1478-84.
Cabral, C., Gonçalves, M. J., Cavaleiro, C., Sales, F., Boyom, F., & Salgueiro, L. (2009). Composition and anti-fungal activity of the essential oil from Cameroonian Vitex rivularis Gürke. Natural Product Research, 23(16), 1478-84. https://doi.org/10.1080/14786410802390106
Cabral C, et al. Composition and Anti-fungal Activity of the Essential Oil From Cameroonian Vitex Rivularis Gürke. Nat Prod Res. 2009;23(16):1478-84. PubMed PMID: 19844822.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition and anti-fungal activity of the essential oil from Cameroonian Vitex rivularis Gürke. AU - Cabral,C, AU - Gonçalves,M J, AU - Cavaleiro,C, AU - Sales,F, AU - Boyom,F, AU - Salgueiro,L, PY - 2009/10/22/entrez PY - 2009/10/22/pubmed PY - 2010/1/14/medline SP - 1478 EP - 84 JF - Natural product research JO - Nat Prod Res VL - 23 IS - 16 N2 - The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of two populations of Vitex rivularis (subgenus Vitex) collected during the flowering phase of the plants was investigated by gas chromatography and gas chromatography/mass spectroscopy. Sesquiterpene hydrocarbons were the main group in both samples, the main compound being germacrene D. This composition is markedly different from that of the other African species, with the exception of Vitex ferruginea subsp. amboniensis, which belongs to the same subgenus as V. rivularis. Minimal inhibitory concentrations (MIC) and minimal lethal concentrations (MLC) were used to evaluate the anti-fungal activity against yeasts and dermatophyte strains. The oils exhibited significant anti-fungal activity against dermatophyte strains with MIC and MLC values ranging from 0.16 to 0.64 microL mL(-1) and 0.32 to 2.5 microL mL(-1), respectively. For some strains, MIC values were similar to MLC values, indicating the fungicidal activity of the oils. Nevertheless, these oils showed low activity against Candida spp. strains. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/19844822/Composition_and_anti_fungal_activity_of_the_essential_oil_from_Cameroonian_Vitex_rivularis_Gürke_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410802390106 DB - PRIME DP - Unbound Medicine ER -