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Omega-3 fatty acids: cardiovascular benefits, sources and sustainability.
Nat Rev Cardiol 2009; 6(12):753-8NR

Abstract

The evidence for the cardioprotective nature of omega-3 fatty acids is abundant, and currently available data indicate that patients with known coronary heart disease should consume at least 1 g daily of long-chain omega-3 fatty acids from either oily fish or fish-oil supplements, and that individuals without disease should consume at least 250-500 mg daily. However, this area of research poses two questions. Firstly, which is the best source of omega-3 fatty acids-fish or fish-oil supplements? Secondly, are recommendations for omega-3 supplementation warranted in view of the rapid depletion of world fish stocks? The argument that eating fish is better than taking fish-oil supplements stems from the fact that several important nutrients, such as vitamin D, selenium, and antioxidants, are missing from the supplements. However, three major prevention trials have clearly indicated that omega-3 fatty acid capsules confer cardiovascular benefits and, therefore, that both are cardioprotective. Sustainable sources of omega-3 fatty acids will need to be identified if long-term cardiovascular risk reduction is to be achieved at the population level.

Authors+Show Affiliations

Mid America Heart Institute and University of Missouri-Kansas City, 64111, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19859067

Citation

Lee, John H., et al. "Omega-3 Fatty Acids: Cardiovascular Benefits, Sources and Sustainability." Nature Reviews. Cardiology, vol. 6, no. 12, 2009, pp. 753-8.
Lee JH, O'Keefe JH, Lavie CJ, et al. Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. Nat Rev Cardiol. 2009;6(12):753-8.
Lee, J. H., O'Keefe, J. H., Lavie, C. J., & Harris, W. S. (2009). Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. Nature Reviews. Cardiology, 6(12), pp. 753-8. doi:10.1038/nrcardio.2009.188.
Lee JH, et al. Omega-3 Fatty Acids: Cardiovascular Benefits, Sources and Sustainability. Nat Rev Cardiol. 2009;6(12):753-8. PubMed PMID: 19859067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Omega-3 fatty acids: cardiovascular benefits, sources and sustainability. AU - Lee,John H, AU - O'Keefe,James H, AU - Lavie,Carl J, AU - Harris,William S, Y1 - 2009/10/27/ PY - 2009/10/28/entrez PY - 2009/10/28/pubmed PY - 2010/1/29/medline SP - 753 EP - 8 JF - Nature reviews. Cardiology JO - Nat Rev Cardiol VL - 6 IS - 12 N2 - The evidence for the cardioprotective nature of omega-3 fatty acids is abundant, and currently available data indicate that patients with known coronary heart disease should consume at least 1 g daily of long-chain omega-3 fatty acids from either oily fish or fish-oil supplements, and that individuals without disease should consume at least 250-500 mg daily. However, this area of research poses two questions. Firstly, which is the best source of omega-3 fatty acids-fish or fish-oil supplements? Secondly, are recommendations for omega-3 supplementation warranted in view of the rapid depletion of world fish stocks? The argument that eating fish is better than taking fish-oil supplements stems from the fact that several important nutrients, such as vitamin D, selenium, and antioxidants, are missing from the supplements. However, three major prevention trials have clearly indicated that omega-3 fatty acid capsules confer cardiovascular benefits and, therefore, that both are cardioprotective. Sustainable sources of omega-3 fatty acids will need to be identified if long-term cardiovascular risk reduction is to be achieved at the population level. SN - 1759-5010 UR - https://www.unboundmedicine.com/medline/citation/19859067/Omega_3_fatty_acids:_cardiovascular_benefits_sources_and_sustainability_ L2 - http://dx.doi.org/10.1038/nrcardio.2009.188 DB - PRIME DP - Unbound Medicine ER -