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Frequency of migraine and the risk of cardiovascular disease for women: limited evidence of an association.
Womens Health (Lond) 2009; 5(6):625-8WH

Abstract

Evaluation of: Kurth T, Schurks M, Logroscino G et al. Migraine frequency and risk of cardiovascular disease in women. Neurology 73, 581-588 (2009). There is substantial evidence that migraine with aura (MA) is associated with ischemic stroke and myocardial infarction in women. The mechanisms of this association are poorly understood. Analysis of data from the Women's Health Study, from 27,798 women over 45 years of age who were initially free of cardiovascular disease, found that women with baseline MA at a frequency of less than monthly had increased risk of major cardiovascular disease (HR: 2.28; 95% CI: 1.70-3.07) relative to women without migraine, and those who reported MA with a frequency of more than weekly had more than four-times the risk of ischemic stroke (HR: 4.25; 95% CI: 1.36-13.29) compared with those without migraine. Low numbers of outcome events in each of the frequency categories and lack of information on migraine frequency during follow-up limit the interpretation of these findings, but they suggest that frequency of migraine may be a moderating factor in the link between MA and cardiovascular disease.

Authors+Show Affiliations

Deakin-Southern Health Nursing Research Centre, Melbourne, Victoria, Australia.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19863465

Citation

Anna, Vibeke, and Mark Woodward. "Frequency of Migraine and the Risk of Cardiovascular Disease for Women: Limited Evidence of an Association." Women's Health (London, England), vol. 5, no. 6, 2009, pp. 625-8.
Anna V, Woodward M. Frequency of migraine and the risk of cardiovascular disease for women: limited evidence of an association. Womens Health (Lond). 2009;5(6):625-8.
Anna, V., & Woodward, M. (2009). Frequency of migraine and the risk of cardiovascular disease for women: limited evidence of an association. Women's Health (London, England), 5(6), pp. 625-8. doi:10.2217/whe.09.63.
Anna V, Woodward M. Frequency of Migraine and the Risk of Cardiovascular Disease for Women: Limited Evidence of an Association. Womens Health (Lond). 2009;5(6):625-8. PubMed PMID: 19863465.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Frequency of migraine and the risk of cardiovascular disease for women: limited evidence of an association. AU - Anna,Vibeke, AU - Woodward,Mark, PY - 2009/10/30/entrez PY - 2009/10/30/pubmed PY - 2010/1/12/medline SP - 625 EP - 8 JF - Women's health (London, England) JO - Womens Health (Lond) VL - 5 IS - 6 N2 - Evaluation of: Kurth T, Schurks M, Logroscino G et al. Migraine frequency and risk of cardiovascular disease in women. Neurology 73, 581-588 (2009). There is substantial evidence that migraine with aura (MA) is associated with ischemic stroke and myocardial infarction in women. The mechanisms of this association are poorly understood. Analysis of data from the Women's Health Study, from 27,798 women over 45 years of age who were initially free of cardiovascular disease, found that women with baseline MA at a frequency of less than monthly had increased risk of major cardiovascular disease (HR: 2.28; 95% CI: 1.70-3.07) relative to women without migraine, and those who reported MA with a frequency of more than weekly had more than four-times the risk of ischemic stroke (HR: 4.25; 95% CI: 1.36-13.29) compared with those without migraine. Low numbers of outcome events in each of the frequency categories and lack of information on migraine frequency during follow-up limit the interpretation of these findings, but they suggest that frequency of migraine may be a moderating factor in the link between MA and cardiovascular disease. SN - 1745-5065 UR - https://www.unboundmedicine.com/medline/citation/19863465/Frequency_of_migraine_and_the_risk_of_cardiovascular_disease_for_women:_limited_evidence_of_an_association_ L2 - http://journals.sagepub.com/doi/full/10.2217/whe.09.63?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -