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Synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N'-(2-alkynylbenzylidene)hydrazides.
Org Biomol Chem. 2009 Nov 21; 7(22):4641-6.OB

Abstract

Diversity-oriented synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N'-(2-alkynylbenzylidene)hydrazide is described. Bromine-mediated electrophilic cyclization, Ag-catalyzed alkyne nucleophilic addition, and palladium-catalyzed cross-coupling reaction were involved in the transformation.

Authors+Show Affiliations

Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19865699

Citation

Chen, Zhiyuan, et al. "Synthesis of Functionalized H-pyrazolo[5,1-a]isoquinolines Via Sequential Reactions of N'-(2-alkynylbenzylidene)hydrazides." Organic & Biomolecular Chemistry, vol. 7, no. 22, 2009, pp. 4641-6.
Chen Z, Su M, Yu X, et al. Synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N'-(2-alkynylbenzylidene)hydrazides. Org Biomol Chem. 2009;7(22):4641-6.
Chen, Z., Su, M., Yu, X., & Wu, J. (2009). Synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N'-(2-alkynylbenzylidene)hydrazides. Organic & Biomolecular Chemistry, 7(22), 4641-6. https://doi.org/10.1039/b914265g
Chen Z, et al. Synthesis of Functionalized H-pyrazolo[5,1-a]isoquinolines Via Sequential Reactions of N'-(2-alkynylbenzylidene)hydrazides. Org Biomol Chem. 2009 Nov 21;7(22):4641-6. PubMed PMID: 19865699.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N'-(2-alkynylbenzylidene)hydrazides. AU - Chen,Zhiyuan, AU - Su,Mingchao, AU - Yu,Xingxin, AU - Wu,Jie, Y1 - 2009/09/16/ PY - 2009/10/30/entrez PY - 2009/10/30/pubmed PY - 2010/2/4/medline SP - 4641 EP - 6 JF - Organic & biomolecular chemistry JO - Org Biomol Chem VL - 7 IS - 22 N2 - Diversity-oriented synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N'-(2-alkynylbenzylidene)hydrazide is described. Bromine-mediated electrophilic cyclization, Ag-catalyzed alkyne nucleophilic addition, and palladium-catalyzed cross-coupling reaction were involved in the transformation. SN - 1477-0539 UR - https://www.unboundmedicine.com/medline/citation/19865699/Synthesis_of_functionalized_H_pyrazolo[51_a]isoquinolines_via_sequential_reactions_of_N'__2_alkynylbenzylidene_hydrazides_ L2 - https://doi.org/10.1039/b914265g DB - PRIME DP - Unbound Medicine ER -
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