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[Study on the constituents of petroleum ether fraction of Buxus microphylla].
Zhong Yao Cai. 2009 Jul; 32(7):1062-4.ZY

Abstract

OBJECTIVE

To study the chemical constituents from the petroleum ether fraction of Buxus microphylla.

METHODS

The petroleum ether fraction of Buxus microphylla was isolated and identified by silica gel column chromatography. And the anticancer activity of different chemical constituents was measured by MTT reduction test.

RESULTS

Eight compounds were isolated and identified as lupeol (1), butulin (3), beta-sitosterol (4), stigmasterol (5), dibutyl phthalate (6), 3beta, 30-dihydroxy-lup-20 (29) ene (7), daucosterol (8). Compound 7 inhibited KB cells' proliferation in a dose-dependent manner.

CONCLUSION

Compounds 2 - 5, 7, 8 are isolated from this genus for the first time. Compound 7 has certainly anticancer effects.

Authors+Show Affiliations

Guilin Medical College, Guilin 541004, China. dzhk110@126.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

19873733

Citation

Dai, Zhi-Kai, et al. "[Study On the Constituents of Petroleum Ether Fraction of Buxus Microphylla]." Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, vol. 32, no. 7, 2009, pp. 1062-4.
Dai ZK, Liang J, Su XJ, et al. [Study on the constituents of petroleum ether fraction of Buxus microphylla]. Zhong Yao Cai. 2009;32(7):1062-4.
Dai, Z. K., Liang, J., Su, X. J., Xu, Q., & Zhang, H. Q. (2009). [Study on the constituents of petroleum ether fraction of Buxus microphylla]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, 32(7), 1062-4.
Dai ZK, et al. [Study On the Constituents of Petroleum Ether Fraction of Buxus Microphylla]. Zhong Yao Cai. 2009;32(7):1062-4. PubMed PMID: 19873733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Study on the constituents of petroleum ether fraction of Buxus microphylla]. AU - Dai,Zhi-Kai, AU - Liang,Jun, AU - Su,Xiao-Jian, AU - Xu,Qing, AU - Zhang,Hui-Qin, PY - 2009/10/31/entrez PY - 2009/10/31/pubmed PY - 2010/2/3/medline SP - 1062 EP - 4 JF - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials JO - Zhong Yao Cai VL - 32 IS - 7 N2 - OBJECTIVE: To study the chemical constituents from the petroleum ether fraction of Buxus microphylla. METHODS: The petroleum ether fraction of Buxus microphylla was isolated and identified by silica gel column chromatography. And the anticancer activity of different chemical constituents was measured by MTT reduction test. RESULTS: Eight compounds were isolated and identified as lupeol (1), butulin (3), beta-sitosterol (4), stigmasterol (5), dibutyl phthalate (6), 3beta, 30-dihydroxy-lup-20 (29) ene (7), daucosterol (8). Compound 7 inhibited KB cells' proliferation in a dose-dependent manner. CONCLUSION: Compounds 2 - 5, 7, 8 are isolated from this genus for the first time. Compound 7 has certainly anticancer effects. SN - 1001-4454 UR - https://www.unboundmedicine.com/medline/citation/19873733/[Study_on_the_constituents_of_petroleum_ether_fraction_of_Buxus_microphylla]_ DB - PRIME DP - Unbound Medicine ER -