Tags

Type your tag names separated by a space and hit enter

[Study on fingerprint of Maodongqing injection by HPLC].
Zhong Yao Cai. 2009 Jul; 32(7):1132-4.ZY

Abstract

OBJECTIVE

To establish the fingerprint of Maodongqing injection by HPLC.

METHODS

The column of ODS-2 Hypersil C18 (4.6 mm x 200 mm, 5 microm) was used. The mobile phase consisted of acetonitrile-0.05% phosphoric acid with gradient elution. The flow rate was 1 mL/min, the column temperature was 30 degrees C, and the detection wavelength was 325 nm.

RESULTS

The fingerprint of Maodongqing injection was established, and 8 samples of different batches of Maodongqing injection were detected. Thirteen peaks in the chromatogram were marked by "Similarity Evaluation System for Chromatographic Fingerprints of Traditional Chinese Medicine (Version 2004 A)". There was a high similarity and each chromatographic peak was obtained with good separation and correlation according to the technical requirements of the fingerprints of Chinese traditional medicine.

CONCLUSION

This method is accurate, reliable and provides a scientific basis for controlling the quality of Maodongqing injection.

Authors+Show Affiliations

Lai S
Guangdong Institute for Drug Control, Guangzhou 510180, China. laishan_77@163.com
Yang LW
No affiliation info available
Ou GD
No affiliation info available
Li YX
No affiliation info available

MeSH

Chromatography, High Pressure LiquidDrugs, Chinese HerbalIlexPlant RootsPlants, MedicinalQuality ControlReproducibility of Results

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

19873743

Citation

Lai, Shan, et al. "[Study On Fingerprint of Maodongqing Injection By HPLC]." Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, vol. 32, no. 7, 2009, pp. 1132-4.
Lai S, Yang LW, Ou GD, et al. [Study on fingerprint of Maodongqing injection by HPLC]. Zhong Yao Cai. 2009;32(7):1132-4.
Lai, S., Yang, L. W., Ou, G. D., & Li, Y. X. (2009). [Study on fingerprint of Maodongqing injection by HPLC]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, 32(7), 1132-4.
Lai S, et al. [Study On Fingerprint of Maodongqing Injection By HPLC]. Zhong Yao Cai. 2009;32(7):1132-4. PubMed PMID: 19873743.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Study on fingerprint of Maodongqing injection by HPLC]. AU - Lai,Shan, AU - Yang,Li-Wei, AU - Ou,Guo-Deng, AU - Li,Yong-Xue, PY - 2009/10/31/entrez PY - 2009/10/31/pubmed PY - 2010/2/3/medline SP - 1132 EP - 4 JF - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials JO - Zhong Yao Cai VL - 32 IS - 7 N2 - OBJECTIVE: To establish the fingerprint of Maodongqing injection by HPLC. METHODS: The column of ODS-2 Hypersil C18 (4.6 mm x 200 mm, 5 microm) was used. The mobile phase consisted of acetonitrile-0.05% phosphoric acid with gradient elution. The flow rate was 1 mL/min, the column temperature was 30 degrees C, and the detection wavelength was 325 nm. RESULTS: The fingerprint of Maodongqing injection was established, and 8 samples of different batches of Maodongqing injection were detected. Thirteen peaks in the chromatogram were marked by "Similarity Evaluation System for Chromatographic Fingerprints of Traditional Chinese Medicine (Version 2004 A)". There was a high similarity and each chromatographic peak was obtained with good separation and correlation according to the technical requirements of the fingerprints of Chinese traditional medicine. CONCLUSION: This method is accurate, reliable and provides a scientific basis for controlling the quality of Maodongqing injection. SN - 1001-4454 UR - https://www.unboundmedicine.com/medline/citation/19873743/[Study_on_fingerprint_of_Maodongqing_injection_by_HPLC]_ DB - PRIME DP - Unbound Medicine ER -