Tags

Type your tag names separated by a space and hit enter

[Particularities of arginase and NO-synthase pathways of L-arginine metabolism in leucocytes of peripheral blood of rats in conditions of chronic x-ray irradiation].
Ukr Biokhim Zh (1999). 2009 Mar-Apr; 81(2):40-8.UB

Abstract

Arginine takes part in many metabolic cell processes. It is not only involved in the dynamic cycle of interconversion with prolin and glutamine but also serves as a precursor for protein, nitric oxide, creatine, polyamines, agmatine and urea synthesis. Particularities of arginase and NO-synthase pathways of L-arginine conversion under the X-ray radiation in the leucocytes-radiosensitive cells of peripheral blood, under the per os administration of L-arginine and L-NAME (NG-nitro-L-arginine methyl ester) to rats were detected. It was shown that both L-arginine (arginase and NO-synthase main substrate) and L-NAME (nonspecific inhibitor of NO-synthase) had a positive correct influence on the organism in case of decreasing of NO overproduction under the X-ray radiation.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ukr

PubMed ID

19873876

Citation

Peretiatko, Iu V., and N O. Sybirna. "[Particularities of Arginase and NO-synthase Pathways of L-arginine Metabolism in Leucocytes of Peripheral Blood of Rats in Conditions of Chronic X-ray Irradiation]." Ukrains'kyi Biokhimichnyi Zhurnal (1999), vol. 81, no. 2, 2009, pp. 40-8.
Peretiatko IuV, Sybirna NO. [Particularities of arginase and NO-synthase pathways of L-arginine metabolism in leucocytes of peripheral blood of rats in conditions of chronic x-ray irradiation]. Ukr Biokhim Zh (1999). 2009;81(2):40-8.
Peretiatko, I. u. V., & Sybirna, N. O. (2009). [Particularities of arginase and NO-synthase pathways of L-arginine metabolism in leucocytes of peripheral blood of rats in conditions of chronic x-ray irradiation]. Ukrains'kyi Biokhimichnyi Zhurnal (1999), 81(2), 40-8.
Peretiatko IuV, Sybirna NO. [Particularities of Arginase and NO-synthase Pathways of L-arginine Metabolism in Leucocytes of Peripheral Blood of Rats in Conditions of Chronic X-ray Irradiation]. Ukr Biokhim Zh (1999). 2009 Mar-Apr;81(2):40-8. PubMed PMID: 19873876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Particularities of arginase and NO-synthase pathways of L-arginine metabolism in leucocytes of peripheral blood of rats in conditions of chronic x-ray irradiation]. AU - Peretiatko,Iu V, AU - Sybirna,N O, PY - 2009/10/31/entrez PY - 2009/10/31/pubmed PY - 2010/4/1/medline SP - 40 EP - 8 JF - Ukrains'kyi biokhimichnyi zhurnal (1999) JO - Ukr Biokhim Zh (1999) VL - 81 IS - 2 N2 - Arginine takes part in many metabolic cell processes. It is not only involved in the dynamic cycle of interconversion with prolin and glutamine but also serves as a precursor for protein, nitric oxide, creatine, polyamines, agmatine and urea synthesis. Particularities of arginase and NO-synthase pathways of L-arginine conversion under the X-ray radiation in the leucocytes-radiosensitive cells of peripheral blood, under the per os administration of L-arginine and L-NAME (NG-nitro-L-arginine methyl ester) to rats were detected. It was shown that both L-arginine (arginase and NO-synthase main substrate) and L-NAME (nonspecific inhibitor of NO-synthase) had a positive correct influence on the organism in case of decreasing of NO overproduction under the X-ray radiation. UR - https://www.unboundmedicine.com/medline/citation/19873876/[Particularities_of_arginase_and_NO_synthase_pathways_of_L_arginine_metabolism_in_leucocytes_of_peripheral_blood_of_rats_in_conditions_of_chronic_x_ray_irradiation]_ DB - PRIME DP - Unbound Medicine ER -