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Efficacy of 308-nm excimer light for Japanese patients with psoriasis.
J Dermatol. 2009 Nov; 36(11):579-82.JD

Abstract

Ultraviolet irradiation therapy, including psoralen and ultraviolet A therapy and narrow-band ultraviolet B (310-312 nm) therapy, is a widely used and highly efficient treatment modality for psoriasis. Therapy with 308-nm excimer light has been reported to be effective for the treatment of psoriasis vulgaris. To evaluate the efficacy of 308-nm excimer light therapy for Japanese psoriasis patients, seven patients (six men and one woman) with plaque-type psoriasis were treated with 308-nm excimer light at 7-14-day intervals. The Psoriasis Severity Index (PSI) was calculated for individual plaques in order to assess the effectiveness of the therapy. A 74.9% mean improvement in the PSI was observed after 10 treatment sessions. These results suggested that targeted irradiation with 308-nm excimer light leads to rapid and selective improvement in plaque-type psoriatic lesions without unnecessary radiation exposure to the surrounding unaffected skin.

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Authors+Show Affiliations

Niwa Y
Department of Dermatology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan. niwa-yu@juntendo.ac.jp
Hasegawa T
No affiliation info available
Ko S
No affiliation info available
Okuyama Y
No affiliation info available
Ohtsuki A
No affiliation info available
Takagi A
No affiliation info available
Ikeda S
No affiliation info available

MeSH

AdultDose-Response Relationship, RadiationFemaleFollow-Up StudiesHumansJapanMaleMiddle AgedPsoriasisQuality of LifeRadiotherapy DosageSampling StudiesSeverity of Illness IndexSkinTreatment OutcomeUltraviolet RaysUltraviolet Therapy

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19878389

Citation

Niwa, Yusuke, et al. "Efficacy of 308-nm Excimer Light for Japanese Patients With Psoriasis." The Journal of Dermatology, vol. 36, no. 11, 2009, pp. 579-82.
Niwa Y, Hasegawa T, Ko S, et al. Efficacy of 308-nm excimer light for Japanese patients with psoriasis. J Dermatol. 2009;36(11):579-82.
Niwa, Y., Hasegawa, T., Ko, S., Okuyama, Y., Ohtsuki, A., Takagi, A., & Ikeda, S. (2009). Efficacy of 308-nm excimer light for Japanese patients with psoriasis. The Journal of Dermatology, 36(11), 579-82. https://doi.org/10.1111/j.1346-8138.2009.00710.x
Niwa Y, et al. Efficacy of 308-nm Excimer Light for Japanese Patients With Psoriasis. J Dermatol. 2009;36(11):579-82. PubMed PMID: 19878389.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of 308-nm excimer light for Japanese patients with psoriasis. AU - Niwa,Yusuke, AU - Hasegawa,Toshio, AU - Ko,Subin, AU - Okuyama,Yasuhiro, AU - Ohtsuki,Akiko, AU - Takagi,Atsushi, AU - Ikeda,Shigaku, PY - 2009/11/3/entrez PY - 2009/11/3/pubmed PY - 2010/1/19/medline SP - 579 EP - 82 JF - The Journal of dermatology JO - J Dermatol VL - 36 IS - 11 N2 - Ultraviolet irradiation therapy, including psoralen and ultraviolet A therapy and narrow-band ultraviolet B (310-312 nm) therapy, is a widely used and highly efficient treatment modality for psoriasis. Therapy with 308-nm excimer light has been reported to be effective for the treatment of psoriasis vulgaris. To evaluate the efficacy of 308-nm excimer light therapy for Japanese psoriasis patients, seven patients (six men and one woman) with plaque-type psoriasis were treated with 308-nm excimer light at 7-14-day intervals. The Psoriasis Severity Index (PSI) was calculated for individual plaques in order to assess the effectiveness of the therapy. A 74.9% mean improvement in the PSI was observed after 10 treatment sessions. These results suggested that targeted irradiation with 308-nm excimer light leads to rapid and selective improvement in plaque-type psoriatic lesions without unnecessary radiation exposure to the surrounding unaffected skin. SN - 1346-8138 UR - https://www.unboundmedicine.com/medline/citation/19878389/Efficacy_of_308_nm_excimer_light_for_Japanese_patients_with_psoriasis_ L2 - https://doi.org/10.1111/j.1346-8138.2009.00710.x DB - PRIME DP - Unbound Medicine ER -