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Efficacy of 308-nm excimer light for Japanese patients with psoriasis.
J Dermatol 2009; 36(11):579-82JD

Abstract

Ultraviolet irradiation therapy, including psoralen and ultraviolet A therapy and narrow-band ultraviolet B (310-312 nm) therapy, is a widely used and highly efficient treatment modality for psoriasis. Therapy with 308-nm excimer light has been reported to be effective for the treatment of psoriasis vulgaris. To evaluate the efficacy of 308-nm excimer light therapy for Japanese psoriasis patients, seven patients (six men and one woman) with plaque-type psoriasis were treated with 308-nm excimer light at 7-14-day intervals. The Psoriasis Severity Index (PSI) was calculated for individual plaques in order to assess the effectiveness of the therapy. A 74.9% mean improvement in the PSI was observed after 10 treatment sessions. These results suggested that targeted irradiation with 308-nm excimer light leads to rapid and selective improvement in plaque-type psoriatic lesions without unnecessary radiation exposure to the surrounding unaffected skin.

Authors+Show Affiliations

Department of Dermatology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, Japan. niwa-yu@juntendo.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19878389

Citation

Niwa, Yusuke, et al. "Efficacy of 308-nm Excimer Light for Japanese Patients With Psoriasis." The Journal of Dermatology, vol. 36, no. 11, 2009, pp. 579-82.
Niwa Y, Hasegawa T, Ko S, et al. Efficacy of 308-nm excimer light for Japanese patients with psoriasis. J Dermatol. 2009;36(11):579-82.
Niwa, Y., Hasegawa, T., Ko, S., Okuyama, Y., Ohtsuki, A., Takagi, A., & Ikeda, S. (2009). Efficacy of 308-nm excimer light for Japanese patients with psoriasis. The Journal of Dermatology, 36(11), pp. 579-82. doi:10.1111/j.1346-8138.2009.00710.x.
Niwa Y, et al. Efficacy of 308-nm Excimer Light for Japanese Patients With Psoriasis. J Dermatol. 2009;36(11):579-82. PubMed PMID: 19878389.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of 308-nm excimer light for Japanese patients with psoriasis. AU - Niwa,Yusuke, AU - Hasegawa,Toshio, AU - Ko,Subin, AU - Okuyama,Yasuhiro, AU - Ohtsuki,Akiko, AU - Takagi,Atsushi, AU - Ikeda,Shigaku, PY - 2009/11/3/entrez PY - 2009/11/3/pubmed PY - 2010/1/19/medline SP - 579 EP - 82 JF - The Journal of dermatology JO - J. Dermatol. VL - 36 IS - 11 N2 - Ultraviolet irradiation therapy, including psoralen and ultraviolet A therapy and narrow-band ultraviolet B (310-312 nm) therapy, is a widely used and highly efficient treatment modality for psoriasis. Therapy with 308-nm excimer light has been reported to be effective for the treatment of psoriasis vulgaris. To evaluate the efficacy of 308-nm excimer light therapy for Japanese psoriasis patients, seven patients (six men and one woman) with plaque-type psoriasis were treated with 308-nm excimer light at 7-14-day intervals. The Psoriasis Severity Index (PSI) was calculated for individual plaques in order to assess the effectiveness of the therapy. A 74.9% mean improvement in the PSI was observed after 10 treatment sessions. These results suggested that targeted irradiation with 308-nm excimer light leads to rapid and selective improvement in plaque-type psoriatic lesions without unnecessary radiation exposure to the surrounding unaffected skin. SN - 1346-8138 UR - https://www.unboundmedicine.com/medline/citation/19878389/Efficacy_of_308_nm_excimer_light_for_Japanese_patients_with_psoriasis_ L2 - https://doi.org/10.1111/j.1346-8138.2009.00710.x DB - PRIME DP - Unbound Medicine ER -