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Experimental study of Love-wave immunosensors based on ZnO/LiTaO3 structures.
Ultrasonics. 2010 Mar; 50(3):411-5.U

Abstract

Experimental study of Love-mode immunosensors based on structures of ZnO/36 degrees YX-LiTaO3 is presented, in which the ZnO films with c-axis (002) orientation have been successfully grown on the 36 degrees YX-LiTaO3 substrates by RF magnetron sputtering technique. Then the Love-mode immunosensors based on the ZnO/36 degrees YX-LiTaO3 structures and monitoring antibody-antigen immunoreactions in aqueous solutions in real time are fabricated. The experimental results show that the optimal thickness of ZnO layers is about 1.20 microm in the structures deposited on 36 degrees YX-LiTaO3 substrates, which is much less than that of SiO2 overlayers about 6 microm. The antibody-antigen immunoreaction experiments also show that the frequency shifts of the sensors with 1.33 microm ZnO films are proportional to the concentration of antigen in solution as the concentration range less than 100 microg/ml.

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Authors+Show Affiliations

Zhou FM
Lab of Modern Acoustics, Institute of Acoustics, Nanjing University, Nanjing 210093, PR China.
Li Z
No affiliation info available
Fan L
No affiliation info available
Zhang SY
No affiliation info available
Shui XJ
No affiliation info available

MeSH

AcousticsBiosensing TechniquesComputer-Aided DesignEquipment DesignEquipment Failure AnalysisImmunoassayLithiumOxidesTantalumZinc Oxide

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19880154

Citation

Zhou, Feng-mei, et al. "Experimental Study of Love-wave Immunosensors Based On ZnO/LiTaO3 Structures." Ultrasonics, vol. 50, no. 3, 2010, pp. 411-5.
Zhou FM, Li Z, Fan L, et al. Experimental study of Love-wave immunosensors based on ZnO/LiTaO3 structures. Ultrasonics. 2010;50(3):411-5.
Zhou, F. M., Li, Z., Fan, L., Zhang, S. Y., & Shui, X. J. (2010). Experimental study of Love-wave immunosensors based on ZnO/LiTaO3 structures. Ultrasonics, 50(3), 411-5. https://doi.org/10.1016/j.ultras.2009.09.024
Zhou FM, et al. Experimental Study of Love-wave Immunosensors Based On ZnO/LiTaO3 Structures. Ultrasonics. 2010;50(3):411-5. PubMed PMID: 19880154.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Experimental study of Love-wave immunosensors based on ZnO/LiTaO3 structures. AU - Zhou,Feng-mei, AU - Li,Zhe, AU - Fan,Li, AU - Zhang,Shu-yi, AU - Shui,Xiu-ji, Y1 - 2009/10/09/ PY - 2009/08/11/received PY - 2009/09/18/accepted PY - 2009/11/3/entrez PY - 2009/11/3/pubmed PY - 2010/2/25/medline SP - 411 EP - 5 JF - Ultrasonics JO - Ultrasonics VL - 50 IS - 3 N2 - Experimental study of Love-mode immunosensors based on structures of ZnO/36 degrees YX-LiTaO3 is presented, in which the ZnO films with c-axis (002) orientation have been successfully grown on the 36 degrees YX-LiTaO3 substrates by RF magnetron sputtering technique. Then the Love-mode immunosensors based on the ZnO/36 degrees YX-LiTaO3 structures and monitoring antibody-antigen immunoreactions in aqueous solutions in real time are fabricated. The experimental results show that the optimal thickness of ZnO layers is about 1.20 microm in the structures deposited on 36 degrees YX-LiTaO3 substrates, which is much less than that of SiO2 overlayers about 6 microm. The antibody-antigen immunoreaction experiments also show that the frequency shifts of the sensors with 1.33 microm ZnO films are proportional to the concentration of antigen in solution as the concentration range less than 100 microg/ml. SN - 1874-9968 UR - https://www.unboundmedicine.com/medline/citation/19880154/Experimental_study_of_Love_wave_immunosensors_based_on_ZnO/LiTaO3_structures_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0041-624X(09)00125-5 DB - PRIME DP - Unbound Medicine ER -