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Spatial risk profiling of Plasmodium falciparum parasitaemia in a high endemicity area in Côte d'Ivoire.
Malar J. 2009 Nov 11; 8:252.MJ

Abstract

BACKGROUND

The objective of this study was to identify demographic, environmental and socioeconomic risk factors and spatial patterns of Plasmodium falciparum parasitaemia in a high endemicity area of Africa, and to specify how this information can facilitate improved malaria control at the district level.

METHODS

A questionnaire was administered to about 4,000 schoolchildren in 55 schools in western Côte d'Ivoire to determine children's socioeconomic status and their habit of sleeping under bed nets. Environmental data were obtained from satellite images, digitized ground maps and a second questionnaire addressed to school directors. Finger prick blood samples were collected and P. falciparum parasitaemia determined under a microscope using standardized, quality-controlled methods. Bayesian variogram models were utilized for spatial risk modelling and mapping of P. falciparum parasitaemia at non-sampled locations, assuming stationary and non-stationary underlying spatial dependence.

RESULTS

Two-thirds of the schoolchildren were infected with P. falciparum and the mean parasitaemia among infected children was 959 parasites/microl of blood. Age, socioeconomic status, not sleeping under a bed net, coverage rate with bed nets and environmental factors (e.g., normalized difference vegetation index, rainfall, land surface temperature and living in close proximity to standing water) were significantly associated with the risk of P. falciparum parasitaemia. After accounting for spatial correlation, age, bed net coverage, rainfall during the main malaria transmission season and distance to rivers remained significant covariates.

CONCLUSION

It is argued that a massive increase in bed net coverage, particularly in villages in close proximity to rivers, in concert with other control measures, is necessary to bring malaria endemicity down to intermediate or low levels.

Authors+Show Affiliations

Département Environnement et Santé, Centre Suisse de Recherches Scientifiques, Abidjan, Côte d'Ivoire. giovanna.raso@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19906295

Citation

Raso, Giovanna, et al. "Spatial Risk Profiling of Plasmodium Falciparum Parasitaemia in a High Endemicity Area in Côte D'Ivoire." Malaria Journal, vol. 8, 2009, p. 252.
Raso G, Silué KD, Vounatsou P, et al. Spatial risk profiling of Plasmodium falciparum parasitaemia in a high endemicity area in Côte d'Ivoire. Malar J. 2009;8:252.
Raso, G., Silué, K. D., Vounatsou, P., Singer, B. H., Yapi, A., Tanner, M., Utzinger, J., & N'Goran, E. K. (2009). Spatial risk profiling of Plasmodium falciparum parasitaemia in a high endemicity area in Côte d'Ivoire. Malaria Journal, 8, 252. https://doi.org/10.1186/1475-2875-8-252
Raso G, et al. Spatial Risk Profiling of Plasmodium Falciparum Parasitaemia in a High Endemicity Area in Côte D'Ivoire. Malar J. 2009 Nov 11;8:252. PubMed PMID: 19906295.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spatial risk profiling of Plasmodium falciparum parasitaemia in a high endemicity area in Côte d'Ivoire. AU - Raso,Giovanna, AU - Silué,Kigbafori D, AU - Vounatsou,Penelope, AU - Singer,Burton H, AU - Yapi,Ahoua, AU - Tanner,Marcel, AU - Utzinger,Jürg, AU - N'Goran,Eliézer K, Y1 - 2009/11/11/ PY - 2009/08/03/received PY - 2009/11/11/accepted PY - 2009/11/13/entrez PY - 2009/11/13/pubmed PY - 2009/12/16/medline SP - 252 EP - 252 JF - Malaria journal JO - Malar J VL - 8 N2 - BACKGROUND: The objective of this study was to identify demographic, environmental and socioeconomic risk factors and spatial patterns of Plasmodium falciparum parasitaemia in a high endemicity area of Africa, and to specify how this information can facilitate improved malaria control at the district level. METHODS: A questionnaire was administered to about 4,000 schoolchildren in 55 schools in western Côte d'Ivoire to determine children's socioeconomic status and their habit of sleeping under bed nets. Environmental data were obtained from satellite images, digitized ground maps and a second questionnaire addressed to school directors. Finger prick blood samples were collected and P. falciparum parasitaemia determined under a microscope using standardized, quality-controlled methods. Bayesian variogram models were utilized for spatial risk modelling and mapping of P. falciparum parasitaemia at non-sampled locations, assuming stationary and non-stationary underlying spatial dependence. RESULTS: Two-thirds of the schoolchildren were infected with P. falciparum and the mean parasitaemia among infected children was 959 parasites/microl of blood. Age, socioeconomic status, not sleeping under a bed net, coverage rate with bed nets and environmental factors (e.g., normalized difference vegetation index, rainfall, land surface temperature and living in close proximity to standing water) were significantly associated with the risk of P. falciparum parasitaemia. After accounting for spatial correlation, age, bed net coverage, rainfall during the main malaria transmission season and distance to rivers remained significant covariates. CONCLUSION: It is argued that a massive increase in bed net coverage, particularly in villages in close proximity to rivers, in concert with other control measures, is necessary to bring malaria endemicity down to intermediate or low levels. SN - 1475-2875 UR - https://www.unboundmedicine.com/medline/citation/19906295/Spatial_risk_profiling_of_Plasmodium_falciparum_parasitaemia_in_a_high_endemicity_area_in_Côte_d'Ivoire_ L2 - https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-8-252 DB - PRIME DP - Unbound Medicine ER -