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Diffuse alveolar hemorrhage as an unusual presentation of systemic lupus erythematosus.
Rheumatol Int 2011; 31(8):1085-7RI

Abstract

Diffuse alveolar hemorrhage (DAH) is rarely seen in patients with systemic lupus erythematosus (SLE), often associated with a poor outcome. It almost affects young women and it is an unusual initial manifestation of SLE. We report a case of SLE presenting with DAH. The patient was a male. He had no history of photosensitivity, malar rash, discoid rash, arthritis, and oral ulcer. Antinuclear antibody, and anti-double stranded DNA (dsDNA) were positive with very high titers, and serum complement levels (C3, C4) were low. He also had renal dysfunction and pericardial effusion. He was diagnosed as DAH due to SLE. He had to undergo hemodialysis for several weeks. DAH and renal dysfunction were improved with intensive treatment including corticosteroid, cyclophosphamide, and mycophenolate mophetil.

Authors+Show Affiliations

Department of Nephrology, Gulhane School of Medicine, Ankara, Turkey. dr.erkansengul@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19908046

Citation

Sengul, Erkan, et al. "Diffuse Alveolar Hemorrhage as an Unusual Presentation of Systemic Lupus Erythematosus." Rheumatology International, vol. 31, no. 8, 2011, pp. 1085-7.
Sengul E, Eyıleten T, Ozcan A, et al. Diffuse alveolar hemorrhage as an unusual presentation of systemic lupus erythematosus. Rheumatol Int. 2011;31(8):1085-7.
Sengul, E., Eyıleten, T., Ozcan, A., Yılmaz, M. I., & Yenıcesu, M. (2011). Diffuse alveolar hemorrhage as an unusual presentation of systemic lupus erythematosus. Rheumatology International, 31(8), pp. 1085-7. doi:10.1007/s00296-009-1227-6.
Sengul E, et al. Diffuse Alveolar Hemorrhage as an Unusual Presentation of Systemic Lupus Erythematosus. Rheumatol Int. 2011;31(8):1085-7. PubMed PMID: 19908046.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffuse alveolar hemorrhage as an unusual presentation of systemic lupus erythematosus. AU - Sengul,Erkan, AU - Eyıleten,Tayfun, AU - Ozcan,Ayhan, AU - Yılmaz,Mahmut Ilker, AU - Yenıcesu,Mujdat, Y1 - 2009/10/27/ PY - 2009/08/20/received PY - 2009/10/07/accepted PY - 2009/11/13/entrez PY - 2009/11/13/pubmed PY - 2011/12/13/medline SP - 1085 EP - 7 JF - Rheumatology international JO - Rheumatol. Int. VL - 31 IS - 8 N2 - Diffuse alveolar hemorrhage (DAH) is rarely seen in patients with systemic lupus erythematosus (SLE), often associated with a poor outcome. It almost affects young women and it is an unusual initial manifestation of SLE. We report a case of SLE presenting with DAH. The patient was a male. He had no history of photosensitivity, malar rash, discoid rash, arthritis, and oral ulcer. Antinuclear antibody, and anti-double stranded DNA (dsDNA) were positive with very high titers, and serum complement levels (C3, C4) were low. He also had renal dysfunction and pericardial effusion. He was diagnosed as DAH due to SLE. He had to undergo hemodialysis for several weeks. DAH and renal dysfunction were improved with intensive treatment including corticosteroid, cyclophosphamide, and mycophenolate mophetil. SN - 1437-160X UR - https://www.unboundmedicine.com/medline/citation/19908046/Diffuse_alveolar_hemorrhage_as_an_unusual_presentation_of_systemic_lupus_erythematosus_ L2 - https://dx.doi.org/10.1007/s00296-009-1227-6 DB - PRIME DP - Unbound Medicine ER -