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A surface acoustic wave-based immunosensing device using a nanocrystalline ZnO film on Si.
J Nanosci Nanotechnol. 2009 Dec; 9(12):7181-5.JN

Abstract

The novelty of this study resides in the fabrication of a bio-sensing device, based on the surface acoustic wave (SAW) on a nanocrystalline ZnO film. The ZnO film was deposited using an rf magnetron sputtering at room temperature on silicon. The deposited films showed the c-axis-oriented crystallite with grain size of approximately 40 nm. The immunosensing device was fabricated using photolithographic protocols on the film. As a model biomolecular recognition and immunosensing, biospecific interaction between a 6-(2,4-dinitrophenyl)aminohexanoic acid (DNP) antigen and its antibody was employed, demonstrating the shifts of resonant frequencies on SAW immunosensing device. The device exhibited a linearity as a function of the antibody concentration in the range of 20-20,000 ng/ml.

Authors+Show Affiliations

Lee DS
IT Convergence Components Lab., Electronics and Telecommunications Research Institute, Daejeon 305350, Korea.
Lee JH
No affiliation info available
Luo J
No affiliation info available
Fu Y
No affiliation info available
Milne WI
No affiliation info available
Maeng S
No affiliation info available
Jung MY
No affiliation info available
Park SH
No affiliation info available
Yoon HC
No affiliation info available

MeSH

AcousticsBiosensing TechniquesCrystallizationEquipment DesignEquipment Failure AnalysisImmunoassayMembranes, ArtificialMicro-Electrical-Mechanical SystemsNanostructuresNanotechnologySiliconSurface PropertiesZinc Oxide

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19908753

Citation

Lee, Dae-Sik, et al. "A Surface Acoustic Wave-based Immunosensing Device Using a Nanocrystalline ZnO Film On Si." Journal of Nanoscience and Nanotechnology, vol. 9, no. 12, 2009, pp. 7181-5.
Lee DS, Lee JH, Luo J, et al. A surface acoustic wave-based immunosensing device using a nanocrystalline ZnO film on Si. J Nanosci Nanotechnol. 2009;9(12):7181-5.
Lee, D. S., Lee, J. H., Luo, J., Fu, Y., Milne, W. I., Maeng, S., Jung, M. Y., Park, S. H., & Yoon, H. C. (2009). A surface acoustic wave-based immunosensing device using a nanocrystalline ZnO film on Si. Journal of Nanoscience and Nanotechnology, 9(12), 7181-5.
Lee DS, et al. A Surface Acoustic Wave-based Immunosensing Device Using a Nanocrystalline ZnO Film On Si. J Nanosci Nanotechnol. 2009;9(12):7181-5. PubMed PMID: 19908753.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A surface acoustic wave-based immunosensing device using a nanocrystalline ZnO film on Si. AU - Lee,Dae-Sik, AU - Lee,Jun Hwang, AU - Luo,Jikui, AU - Fu,Yongqing, AU - Milne,William I, AU - Maeng,Sunglyul, AU - Jung,Mun Yeon, AU - Park,Sun Hee, AU - Yoon,Hyun C, PY - 2009/11/14/entrez PY - 2009/11/17/pubmed PY - 2009/12/16/medline SP - 7181 EP - 5 JF - Journal of nanoscience and nanotechnology JO - J Nanosci Nanotechnol VL - 9 IS - 12 N2 - The novelty of this study resides in the fabrication of a bio-sensing device, based on the surface acoustic wave (SAW) on a nanocrystalline ZnO film. The ZnO film was deposited using an rf magnetron sputtering at room temperature on silicon. The deposited films showed the c-axis-oriented crystallite with grain size of approximately 40 nm. The immunosensing device was fabricated using photolithographic protocols on the film. As a model biomolecular recognition and immunosensing, biospecific interaction between a 6-(2,4-dinitrophenyl)aminohexanoic acid (DNP) antigen and its antibody was employed, demonstrating the shifts of resonant frequencies on SAW immunosensing device. The device exhibited a linearity as a function of the antibody concentration in the range of 20-20,000 ng/ml. SN - 1533-4880 UR - https://www.unboundmedicine.com/medline/citation/19908753/A_surface_acoustic_wave_based_immunosensing_device_using_a_nanocrystalline_ZnO_film_on_Si_ DB - PRIME DP - Unbound Medicine ER -