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Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge?
Acta Paediatr. 2010 Nov; 99(11):1661-5.AP

Abstract

AIM

The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy.

METHODS

Thirty five children with severe disabilities with cerebral palsy who started continuous intrathecal baclofen therapy (CITB) were followed for 18 months. Pain, number of awakenings during night, spasticity, GMFM-66 scores and PEDI scores were recorded the day before pump implantation and after 6 and 18 months of treatment respectively.

RESULTS

Introduction of CITB was associated with changes across all ICF dimensions. Reduced pain and improved sleep occurred within 6 months of treatment. Social function improved within 6 months and continued to improve until 18 months of CITB. Mobility also improved, but with a latency.

CONCLUSION

There seems to be a sequence of changes after introduction of continuous intrathecal baclofen in a child with cerebral palsy that may guide the multidisciplinary team in their timing of therapy during post-surgical follow-up.

Authors+Show Affiliations

Department of Paediatrics, Oslo University Hospital, Oslo, Norway. kjersti.ramstad@rikshospitalet.noNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19912148

Citation

Ramstad, K, et al. "Continuous Intrathecal Baclofen Therapy in Children With Cerebral Palsy - when Does Improvement Emerge?" Acta Paediatrica (Oslo, Norway : 1992), vol. 99, no. 11, 2010, pp. 1661-5.
Ramstad K, Jahnsen R, Lofterod B, et al. Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge? Acta Paediatr. 2010;99(11):1661-5.
Ramstad, K., Jahnsen, R., Lofterod, B., & Skjeldal, O. H. (2010). Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge? Acta Paediatrica (Oslo, Norway : 1992), 99(11), 1661-5. https://doi.org/10.1111/j.1651-2227.2009.01596.x
Ramstad K, et al. Continuous Intrathecal Baclofen Therapy in Children With Cerebral Palsy - when Does Improvement Emerge. Acta Paediatr. 2010;99(11):1661-5. PubMed PMID: 19912148.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge? AU - Ramstad,K, AU - Jahnsen,R, AU - Lofterod,B, AU - Skjeldal,O H, PY - 2009/11/17/entrez PY - 2009/11/17/pubmed PY - 2011/3/4/medline SP - 1661 EP - 5 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr. VL - 99 IS - 11 N2 - AIM: The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy. METHODS: Thirty five children with severe disabilities with cerebral palsy who started continuous intrathecal baclofen therapy (CITB) were followed for 18 months. Pain, number of awakenings during night, spasticity, GMFM-66 scores and PEDI scores were recorded the day before pump implantation and after 6 and 18 months of treatment respectively. RESULTS: Introduction of CITB was associated with changes across all ICF dimensions. Reduced pain and improved sleep occurred within 6 months of treatment. Social function improved within 6 months and continued to improve until 18 months of CITB. Mobility also improved, but with a latency. CONCLUSION: There seems to be a sequence of changes after introduction of continuous intrathecal baclofen in a child with cerebral palsy that may guide the multidisciplinary team in their timing of therapy during post-surgical follow-up. SN - 1651-2227 UR - https://www.unboundmedicine.com/medline/citation/19912148/Continuous_intrathecal_baclofen_therapy_in_children_with_cerebral_palsy___when_does_improvement_emerge L2 - https://doi.org/10.1111/j.1651-2227.2009.01596.x DB - PRIME DP - Unbound Medicine ER -