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Alcohol consumption in patients with colorectal adenomatous polyps.
Gut. 1991 Jan; 32(1):70-2.Gut

Abstract

The risk of developing colorectal adenomatous polyps is probably increased by a variety of dietary and environmental factors. We found an association with current alcohol and cigarette consumption. The risk of polyps was increased three times in drinkers who did not smoke and two times in smokers who did not drink, with those who both drank and smoked having 12 times the risk of total abstainers. Since colonic adenomatous polyps are generally regarded as premalignant lesions, these results lend support to the view that alcohol consumption may be an important factor in the pathogenesis of colorectal neoplasia, thus reinforcing the proposed polyp/carcinoma sequence in colorectal carcinogenesis. The role of smoking, however, is less clear particularly since the lack of association of colorectal carcinoma and smoking has been reported in many other studies.

Authors+Show Affiliations

Department of Medicine, St James's University Hospital, Leeds.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1991640

Citation

Cope, G F., et al. "Alcohol Consumption in Patients With Colorectal Adenomatous Polyps." Gut, vol. 32, no. 1, 1991, pp. 70-2.
Cope GF, Wyatt JI, Pinder IF, et al. Alcohol consumption in patients with colorectal adenomatous polyps. Gut. 1991;32(1):70-2.
Cope, G. F., Wyatt, J. I., Pinder, I. F., Lee, P. N., Heatley, R. V., & Kelleher, J. (1991). Alcohol consumption in patients with colorectal adenomatous polyps. Gut, 32(1), 70-2.
Cope GF, et al. Alcohol Consumption in Patients With Colorectal Adenomatous Polyps. Gut. 1991;32(1):70-2. PubMed PMID: 1991640.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption in patients with colorectal adenomatous polyps. AU - Cope,G F, AU - Wyatt,J I, AU - Pinder,I F, AU - Lee,P N, AU - Heatley,R V, AU - Kelleher,J, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 70 EP - 2 JF - Gut JO - Gut VL - 32 IS - 1 N2 - The risk of developing colorectal adenomatous polyps is probably increased by a variety of dietary and environmental factors. We found an association with current alcohol and cigarette consumption. The risk of polyps was increased three times in drinkers who did not smoke and two times in smokers who did not drink, with those who both drank and smoked having 12 times the risk of total abstainers. Since colonic adenomatous polyps are generally regarded as premalignant lesions, these results lend support to the view that alcohol consumption may be an important factor in the pathogenesis of colorectal neoplasia, thus reinforcing the proposed polyp/carcinoma sequence in colorectal carcinogenesis. The role of smoking, however, is less clear particularly since the lack of association of colorectal carcinoma and smoking has been reported in many other studies. SN - 0017-5749 UR - https://www.unboundmedicine.com/medline/citation/1991640/Alcohol_consumption_in_patients_with_colorectal_adenomatous_polyps_ L2 - https://gut.bmj.com/lookup/pmidlookup?view=long&pmid=1991640 DB - PRIME DP - Unbound Medicine ER -