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Maternal and fetal outcome of pregnancy complicated by HELLP syndrome.
J Matern Fetal Neonatal Med. 2009 Dec; 22(12):1140-3.JM

Abstract

OBJECTIVE

The study evaluated the maternal and fetal outcome in 64 pregnancies complicated by HELLP syndrome.

METHODS

A retrospective analysis of the medical records was performed of patients with HELLP syndrome managed at this tertiary Obstetric unit between January 1996 and December 2005, who were admitted for preeclamsia/eclampsia and had documented evidence of hemolysis, elevated liver enzymes and low platelet count. Maternal and neonatal complications were recorded and analyzed.

RESULTS

The incidence of HELLP syndrome in the study was 8.3%. Mean gestational age at delivery was 32.4 +/- 4.2 weeks and mean birth weight was 1851 +/- 810 g. Forty-two percent of the patients had deliveries <32 weeks and 28% IUGR. Respiratory distress syndrome was the main indication for NICU admissions (33.9%). The PNM rate was 20%. Maternal morbidity rate was 34%. The most common maternal complications were abruptio placentae (36.4%) and DIC (31.8%). There was no maternal death.

CONCLUSION

Once the diagnosis of HELLP syndrome is confirmed, the management depends on several obstetric and maternal variables like gestational age, severity of laboratory abnormalities and fetal status. As soon as the maternal condition is stabilized and fetal assessment is obtained, prompt delivery of the fetus is indicated. It is not yet established whether expectant management in preterm pregnancies with HELLP syndrome would improve perinatal outcome.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, College of Medicine, King Faisal University, Dammam, Saudi Arabia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19916711

Citation

Gasem, Turki, et al. "Maternal and Fetal Outcome of Pregnancy Complicated By HELLP Syndrome." The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 22, no. 12, 2009, pp. 1140-3.
Gasem T, Al Jama FE, Burshaid S, et al. Maternal and fetal outcome of pregnancy complicated by HELLP syndrome. J Matern Fetal Neonatal Med. 2009;22(12):1140-3.
Gasem, T., Al Jama, F. E., Burshaid, S., Rahman, J., Al Suleiman, S. A., & Rahman, M. S. (2009). Maternal and fetal outcome of pregnancy complicated by HELLP syndrome. The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 22(12), 1140-3. https://doi.org/10.3109/14767050903019627
Gasem T, et al. Maternal and Fetal Outcome of Pregnancy Complicated By HELLP Syndrome. J Matern Fetal Neonatal Med. 2009;22(12):1140-3. PubMed PMID: 19916711.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Maternal and fetal outcome of pregnancy complicated by HELLP syndrome. AU - Gasem,Turki, AU - Al Jama,Fathia E, AU - Burshaid,Sameera, AU - Rahman,Jessica, AU - Al Suleiman,Suleiman A, AU - Rahman,Mohammad S, PY - 2009/11/18/entrez PY - 2009/11/18/pubmed PY - 2010/2/6/medline SP - 1140 EP - 3 JF - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JO - J Matern Fetal Neonatal Med VL - 22 IS - 12 N2 - OBJECTIVE: The study evaluated the maternal and fetal outcome in 64 pregnancies complicated by HELLP syndrome. METHODS: A retrospective analysis of the medical records was performed of patients with HELLP syndrome managed at this tertiary Obstetric unit between January 1996 and December 2005, who were admitted for preeclamsia/eclampsia and had documented evidence of hemolysis, elevated liver enzymes and low platelet count. Maternal and neonatal complications were recorded and analyzed. RESULTS: The incidence of HELLP syndrome in the study was 8.3%. Mean gestational age at delivery was 32.4 +/- 4.2 weeks and mean birth weight was 1851 +/- 810 g. Forty-two percent of the patients had deliveries <32 weeks and 28% IUGR. Respiratory distress syndrome was the main indication for NICU admissions (33.9%). The PNM rate was 20%. Maternal morbidity rate was 34%. The most common maternal complications were abruptio placentae (36.4%) and DIC (31.8%). There was no maternal death. CONCLUSION: Once the diagnosis of HELLP syndrome is confirmed, the management depends on several obstetric and maternal variables like gestational age, severity of laboratory abnormalities and fetal status. As soon as the maternal condition is stabilized and fetal assessment is obtained, prompt delivery of the fetus is indicated. It is not yet established whether expectant management in preterm pregnancies with HELLP syndrome would improve perinatal outcome. SN - 1476-4954 UR - https://www.unboundmedicine.com/medline/citation/19916711/Maternal_and_fetal_outcome_of_pregnancy_complicated_by_HELLP_syndrome_ DB - PRIME DP - Unbound Medicine ER -