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Terbinafine-induced acute generalized exanthematous pustulosis (AGEP) responsive to high dose intravenous corticosteroid.
Dermatol Online J. 2009 Sep 15; 15(9):8.DO

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a febrile pustular drug eruption. Terbinafine, an allylamine fungicidial agent, is the most common anti-mycotic associated with AGEP. Here, we report a case of terbinafine-induced AGEP that was recalcitrant to oral corticosteroid but responsive to high-dose intravenous corticosteroid.

Authors+Show Affiliations

Ibrahimi OA
Harvard Medical School, Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Gunawardane N
No affiliation info available
Sepehr A
No affiliation info available
Reynolds RV
No affiliation info available

MeSH

Acute Generalized Exanthematous PustulosisAnti-Inflammatory AgentsAntifungal AgentsClobetasolDiphenhydramineFatigueFemaleHumansImmunosuppressive AgentsInfusions, IntravenousMethylprednisoloneMiddle AgedNaphthalenesOnychomycosisPainPrednisoneTerbinafine

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19930995

Citation

Ibrahimi, Omar A., et al. "Terbinafine-induced Acute Generalized Exanthematous Pustulosis (AGEP) Responsive to High Dose Intravenous Corticosteroid." Dermatology Online Journal, vol. 15, no. 9, 2009, p. 8.
Ibrahimi OA, Gunawardane N, Sepehr A, et al. Terbinafine-induced acute generalized exanthematous pustulosis (AGEP) responsive to high dose intravenous corticosteroid. Dermatol Online J. 2009;15(9):8.
Ibrahimi, O. A., Gunawardane, N., Sepehr, A., & Reynolds, R. V. (2009). Terbinafine-induced acute generalized exanthematous pustulosis (AGEP) responsive to high dose intravenous corticosteroid. Dermatology Online Journal, 15(9), 8.
Ibrahimi OA, et al. Terbinafine-induced Acute Generalized Exanthematous Pustulosis (AGEP) Responsive to High Dose Intravenous Corticosteroid. Dermatol Online J. 2009 Sep 15;15(9):8. PubMed PMID: 19930995.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Terbinafine-induced acute generalized exanthematous pustulosis (AGEP) responsive to high dose intravenous corticosteroid. AU - Ibrahimi,Omar A, AU - Gunawardane,Nilanthi, AU - Sepehr,Alireza, AU - Reynolds,Rachel V, Y1 - 2009/09/15/ PY - 2009/11/26/entrez PY - 2009/11/26/pubmed PY - 2010/2/13/medline SP - 8 EP - 8 JF - Dermatology online journal JO - Dermatol Online J VL - 15 IS - 9 N2 - Acute generalized exanthematous pustulosis (AGEP) is a febrile pustular drug eruption. Terbinafine, an allylamine fungicidial agent, is the most common anti-mycotic associated with AGEP. Here, we report a case of terbinafine-induced AGEP that was recalcitrant to oral corticosteroid but responsive to high-dose intravenous corticosteroid. SN - 1087-2108 UR - https://www.unboundmedicine.com/medline/citation/19930995/Terbinafine_induced_acute_generalized_exanthematous_pustulosis__AGEP__responsive_to_high_dose_intravenous_corticosteroid_ DB - PRIME DP - Unbound Medicine ER -