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Chronic kidney disease as a predictor of coronary lesion morphology.
Angiology. 2010 May; 61(4):344-9.A

Abstract

Coronary artery disease (CAD) is the main cause of death in patients with chronic kidney disease (CKD). We investigated whether CKD stage affected coronary lesion morphology in patients with established CAD. Coronary angiograms of 264 patients were evaluated. Chronic kidney disease was staged using the estimated glomerular filtration rate (eGFR) from the serum creatinine prior to coronary angiography. Patients were divided into 3 groups: dialysis or severe decrease in GFR <30 mL/min per 1.73 m(2) (group 1; n = 60), patients with moderate kidney failure (group 2; n = 116), and patients with normal renal function or mild decrease in GFR (group 3; n = 88). The likelihood of CAD and lesion complexity increased with decreasing eGFR (P = .001). Patients with CKD also had more significant CAD. The risk of significant coronary obstruction and lesion complexity increased progressively with decreasing eGFR. The eGFR may predict lesion complexity among patients with CKD undergoing coronary angiography.

Authors+Show Affiliations

Department of Cardiology, Istanbul University Institute of Cardiology, Haseki, Aksaray, Istanbul, Turkey. kadriye11@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19939822

Citation

Kilickesmez, Kadriye Orta, et al. "Chronic Kidney Disease as a Predictor of Coronary Lesion Morphology." Angiology, vol. 61, no. 4, 2010, pp. 344-9.
Kilickesmez KO, Abaci O, Okcun B, et al. Chronic kidney disease as a predictor of coronary lesion morphology. Angiology. 2010;61(4):344-9.
Kilickesmez, K. O., Abaci, O., Okcun, B., Kocas, C., Baskurt, M., Arat, A., Ersanli, M., & Gurmen, T. (2010). Chronic kidney disease as a predictor of coronary lesion morphology. Angiology, 61(4), 344-9. https://doi.org/10.1177/0003319709351875
Kilickesmez KO, et al. Chronic Kidney Disease as a Predictor of Coronary Lesion Morphology. Angiology. 2010;61(4):344-9. PubMed PMID: 19939822.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chronic kidney disease as a predictor of coronary lesion morphology. AU - Kilickesmez,Kadriye Orta, AU - Abaci,Okay, AU - Okcun,Baris, AU - Kocas,Cuneyt, AU - Baskurt,Murat, AU - Arat,Alev, AU - Ersanli,Murat, AU - Gurmen,Tevfik, Y1 - 2009/11/24/ PY - 2009/11/27/entrez PY - 2009/11/27/pubmed PY - 2010/7/16/medline SP - 344 EP - 9 JF - Angiology JO - Angiology VL - 61 IS - 4 N2 - Coronary artery disease (CAD) is the main cause of death in patients with chronic kidney disease (CKD). We investigated whether CKD stage affected coronary lesion morphology in patients with established CAD. Coronary angiograms of 264 patients were evaluated. Chronic kidney disease was staged using the estimated glomerular filtration rate (eGFR) from the serum creatinine prior to coronary angiography. Patients were divided into 3 groups: dialysis or severe decrease in GFR <30 mL/min per 1.73 m(2) (group 1; n = 60), patients with moderate kidney failure (group 2; n = 116), and patients with normal renal function or mild decrease in GFR (group 3; n = 88). The likelihood of CAD and lesion complexity increased with decreasing eGFR (P = .001). Patients with CKD also had more significant CAD. The risk of significant coronary obstruction and lesion complexity increased progressively with decreasing eGFR. The eGFR may predict lesion complexity among patients with CKD undergoing coronary angiography. SN - 1940-1574 UR - https://www.unboundmedicine.com/medline/citation/19939822/Chronic_kidney_disease_as_a_predictor_of_coronary_lesion_morphology_ L2 - https://journals.sagepub.com/doi/10.1177/0003319709351875?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -