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Phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from children with acute respiratory infections in Yamagata, Japan.
Virus Res. 2010 Feb; 147(2):265-74.VR

Abstract

We performed phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from 76 children with acute respiratory infection in Yamagata prefecture, Japan during the period 2003-2007. Phylogenetic trees based on the nucleotide and amino acid sequences of the VP4/VP2 coding region showed that the present strains could be classified into 11 and 8 clusters, respectively. The homology among the present strains ranged from 66.6% to 100% at the nucleotide level and 84.7% to 100% at the amino acid level. The interspecies distance (mean+/-standard deviation) was calculated to be 0.235+/-0.048 at the nucleotide level and 0.076+/-0.033 at the amino acid level. In addition, the phylogenetic trees created based on the nucleotide and amino acid sequences showed that HRV-A strains belonging to some clusters were associated with both upper respiratory infection and wheezy bronchiolitis, while other strains were associated with upper respiratory infection alone. These results suggest that the present HRV-A isolates had a wide nucleotide divergence and were associated with acute respiratory infection, including upper respiratory infection and wheezy bronchiolitis, in Yamagata prefecture, Japan during the investigation period.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Mizuta K
Yamagata Prefectural Institute of Public Health, 1-6-6 Toka-machi, Yamagata-shi, Yamagata 990-0031, Japan.
Hirata A
No affiliation info available
Suto A
No affiliation info available
Aoki Y
No affiliation info available
Ahiko T
No affiliation info available
Itagaki T
No affiliation info available
Tsukagoshi H
No affiliation info available
Morita Y
No affiliation info available
Obuchi M
No affiliation info available
Akiyama M
No affiliation info available
Okabe N
No affiliation info available
Noda M
No affiliation info available
Tashiro M
No affiliation info available
Kimura H
No affiliation info available

MeSH

AdolescentChildChild, PreschoolCluster AnalysisFemaleHumansInfantJapanMaleMolecular EpidemiologyMolecular Sequence DataPhylogenyPicornaviridae InfectionsRNA, ViralRespiratory Tract InfectionsRhinovirusSequence Analysis, DNASequence Homology, Amino AcidSequence Homology, Nucleic AcidViral Structural Proteins

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19945490

Citation

Mizuta, Katsumi, et al. "Phylogenetic and Cluster Analysis of Human Rhinovirus Species a (HRV-A) Isolated From Children With Acute Respiratory Infections in Yamagata, Japan." Virus Research, vol. 147, no. 2, 2010, pp. 265-74.
Mizuta K, Hirata A, Suto A, et al. Phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from children with acute respiratory infections in Yamagata, Japan. Virus Res. 2010;147(2):265-74.
Mizuta, K., Hirata, A., Suto, A., Aoki, Y., Ahiko, T., Itagaki, T., Tsukagoshi, H., Morita, Y., Obuchi, M., Akiyama, M., Okabe, N., Noda, M., Tashiro, M., & Kimura, H. (2010). Phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from children with acute respiratory infections in Yamagata, Japan. Virus Research, 147(2), 265-74. https://doi.org/10.1016/j.virusres.2009.11.011
Mizuta K, et al. Phylogenetic and Cluster Analysis of Human Rhinovirus Species a (HRV-A) Isolated From Children With Acute Respiratory Infections in Yamagata, Japan. Virus Res. 2010;147(2):265-74. PubMed PMID: 19945490.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from children with acute respiratory infections in Yamagata, Japan. AU - Mizuta,Katsumi, AU - Hirata,Asumi, AU - Suto,Asuka, AU - Aoki,Yoko, AU - Ahiko,Tadayuki, AU - Itagaki,Tsutomu, AU - Tsukagoshi,Hiroyuki, AU - Morita,Yukio, AU - Obuchi,Masatsugu, AU - Akiyama,Miho, AU - Okabe,Nobuhiko, AU - Noda,Masahiro, AU - Tashiro,Masato, AU - Kimura,Hirokazu, Y1 - 2009/11/27/ PY - 2009/07/22/received PY - 2009/11/13/revised PY - 2009/11/19/accepted PY - 2009/12/1/entrez PY - 2009/12/1/pubmed PY - 2010/2/18/medline SP - 265 EP - 74 JF - Virus research JO - Virus Res VL - 147 IS - 2 N2 - We performed phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from 76 children with acute respiratory infection in Yamagata prefecture, Japan during the period 2003-2007. Phylogenetic trees based on the nucleotide and amino acid sequences of the VP4/VP2 coding region showed that the present strains could be classified into 11 and 8 clusters, respectively. The homology among the present strains ranged from 66.6% to 100% at the nucleotide level and 84.7% to 100% at the amino acid level. The interspecies distance (mean+/-standard deviation) was calculated to be 0.235+/-0.048 at the nucleotide level and 0.076+/-0.033 at the amino acid level. In addition, the phylogenetic trees created based on the nucleotide and amino acid sequences showed that HRV-A strains belonging to some clusters were associated with both upper respiratory infection and wheezy bronchiolitis, while other strains were associated with upper respiratory infection alone. These results suggest that the present HRV-A isolates had a wide nucleotide divergence and were associated with acute respiratory infection, including upper respiratory infection and wheezy bronchiolitis, in Yamagata prefecture, Japan during the investigation period. SN - 1872-7492 UR - https://www.unboundmedicine.com/medline/citation/19945490/Phylogenetic_and_cluster_analysis_of_human_rhinovirus_species_A__HRV_A__isolated_from_children_with_acute_respiratory_infections_in_Yamagata_Japan_ DB - PRIME DP - Unbound Medicine ER -